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Adrenal Bone Cardiovascular Diabetes Endocrine-Disrupting Chemicals Endocrine-Related Cancer Metabolism Neuroendocrinology Obesity Reproduction Steroid and Steroidogenesis Thyroid

Diabetes Islets

Islets Insulin BetaCells Pancreas Glucose Hyperglycemia Hypoglycemia Insulinoma Glucagon IGF Type 1 Type 2

Type 1 and 2 diabetes could be treated with eye implant

Society congratulates our new Early Career Grant awardees

Society congratulates our new Early Career Grant awardees

ESPE News - Issue 43 - Diabetes Technology

ESPE News - Issue 43 - Diabetes Technology

Pancreatic islets are the ‘glucostat’ of the body

Research Fellow – Full-time (Fixed Term) at the Institute of Metabolism and Systems Research (IMSR), University of Birmingham

Type 1 diabetes treatment could end need for insulin injections

Protein that repels immune cells protects transplanted pancreatic islets from rejection

Young vessels rejuvenate aged insulin-producing beta cells

New source of fat tissue stem cells found (MedPage Today, 8 May 2014)

Imaging autoimmune diabetes (Medical News Today, 30 January 2014)

Link between inherited endocrine tumour syndrome and much-studied cell pathway (EurekAlert, 24 April 2013)

Postdoctoral Fellowship in Diabetes Research – Cellular Metabolism, Malmö, Sweden

Expression of selenoprotein P in beta cells

IL6 modulates β -cell metabolism and function

Research Assistant, University of Oxford

Postdoctoral position 'electrophysiology of islets of Langerhans', Dresden, Germany

Postdoctoral Position in Molecular Endocrinology, Stockholm, Sweden

Role of GPR55 in metabolism

Chronic glucokinase activation

Researcher in Experimental Endocrinology and Genetics, Sweden

Exercise and insulin secretion

Research Technician - King's College London Diabetes Research Group

Low protein diet delays onset of diabetes

European Association for the Study of Diabetes - Albert Renold Prize Lecture 2009

Postdoctoral position in Molecular Endocrinology, Stockholm, Sweden

Postdoctoral Fellow, University of Alberta, Canada

LEA29Y expression in transgenic porcine islets prevents islet graft rejection in humanized mice with...

Resource not read: Query You and Your Hormones

Preferential amyloid deposit formation in the most bloodperfused islets

SEX-BASED IMPACT OF PANCREATIC ISLET STRESSORS IN GluCreERT2/Rosa26-eYFP MICE

miR-132 improves β-cell function in mice

Low thyroid hormone may alter fetal pancreas development

Unravelling new type 2 diabetes regulatory links with 3D chromatin topology analysis and CRISPR-Cas9 perturbations

EndoConn Summer 2017 paper

CLEC11A IMPROVES INSULIN SECRETION AND PROMOTES HUMAN β-CELL PROLIFERATION

Images in Endocrinology

SEX MATTERS: WHY EXPERIMENTS IN DIABETES MUST INCLUDE MALES AND FEMALES

Advance your research: equip your lab using society funds

Towards self-management in type 1 diabetes

Endocrinologist 137 Web

Endocrinologist 137 Web.pdf (1)

Better together: the Specialist Endocrinology clinical reference group

LAYING FOUNDATIONS FOR THE FUTURE: SOCIETY SUMMER STUDENTSHIPS

EARLY CAREER SCIENTIST: STUDYING RARE DISEASES TO UNCOVER THE MECHANISMS REGULATING HUMAN PANCREATIC DEVELOPMENT

Welcome to Starling House: the Society’s new home celebrates the birth of endocrinology

Endocrine Networks: Metabolic and Obesity update

Where next after ‘biggest and best’? Public engagement with schools

Progress in understanding pancreatic NETs

Endocrinologist 126

Endocrinologist 150 Web

Endocrinologist 123 Web

Endocrinologist 130 Web

Endocrinologist 151 Final

The Endocrinologist 116 Web FINAL v2.pdf

The Endocrinologist 115 Web FINAL.pdf

ScreenSummerEndoComplete.pdf

Endocrinologist 135 Web

Endocrinologist 149 Web

Endocrinologist 149 Web

Endocrinologist 145 Web

Endocrinologist 124 Web

Endocrinologist 129 Web

Endocrinologist 143 Web

The Endocrinologist Autumn 14 -website.pdf

The Endocrinologist 117 Web.pdf

Endocrinologist 127 Web

The Endocrinologist 127 Web.pdf

Endocrinologist 134 Web Updated

The Endocrinologist spring14 web version FINAL.pdf

Endocrinologist 131 Web Updated

Insulin receptor activation inhibits insulin secretion from human islets of Langerhans

Focal Congenital Hyperinsulinism in Infancy is Directly Linked to Increased Numbers of Islet Pancreatic Polypeptide Cells in Islets.

Innervation and vascularization into islets of langerhans in the presence or absence of proglucagon-derived peptides

Arachidonic acid and insulin release from human islets of Langerhans

Glucagon-like peptide-1 stimulates insulin secretion and then somatostatin secretion in rat islets

LEA29Y expression in transgenic porcine islets prevents islet graft rejection in humanized mice without systemic immunosuppressive therapy

2.18. Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice

TGFß1 signalling in human insulinomas compared with human islets.

Exenatide protects pancreatic islets against brain death-induced inflammation and viability loss

Investigating mesenchymal stromal cell mediated support of islets after exposure to transplantation related stressors

Transcriptome profiles of human pancreatic islets following transient ischemia identify inflammatory and cell death responses

Paradoxical effects of GABA on glucose-stimulated insulin secretion from isolated islets in rat

Activation of peroxisome-proliferator-activated receptor (PPAR) alpha reverses high-fat induced insulin hypersecretion in perifused pancreatic islets

Islet transplantation

Regulation and impact of changes in PPARalpha expression on glucose-stimulated insulin secretion by pancreatic islets

Immunohistochemical localisation of 11β-hydroxysteroid dehydrogenase type 1 in murine pancreatic islets

2.5. SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism.

The effect of gestational hypothyroidism on insulin secretion from isolated islets of adult offspring in male rats

Expression of beta2 adrenergic receptors in pancreatic islets of metabolic syndrome induced C57BL/6J Mice

Islet transplantation and regeneration

Transcriptional profiles explain insulin hypersecretion following chronic adrenergic stimulation in foetal sheep islets

10.17. Efficacy of glucagon-like peptide-1 and estrogen dual agonist in pancreatic islets protection and preclinical models of insulin-deficient diabetes

Modulation of EGFR expression to increase islet transplantation success

The progesterone metabolite epiallopregnanolone sulphate induces glucose-stimulated insulin secretion from human and mouse islets and is reduced in gestational diabetes mellitus

Islet cell transplantation: an update

Pancreatic islet transplantation

Somatostatin producing cells are significantly decreased in insulinoma islets of multiple endocrine neoplasia type 1 (MEN1) knockout mice: implication for pancreatic proliferation rates

Function of the calcium-sensing receptor in insulin-secreting MIN6 cells and human islets of Langerhans

Altered islet architecture in congenital hyperinsulinism in infancy

Diazoxide pretreatment improves pancreatic islet survival <em>in vitro</em> and functionality <em>in vivo</em>

Activation of GPR120 by lipid agonists modulates glucagon secretion in pancreatic islets and improves glucose tolerance in mice

Hormonal control of β-cell proliferation in fetal ovine pancreatic islets <em>in vitro</em>

A Selective Nonpeptide Somatostatin Receptor 5 (SST5) Agonist Effectively Decreases Insulin Secretion in a KATPHI Mouse Model and in Human HI Islets

Improvement of human pancreatic islet quality after co-culture with human adipose-derived stem cells

Islet transplantation: way to go!

10.15. Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes

The "other" islet cells - state of the art for endocrinologists

Effects of perinatal tributyltin exposure in Wistar rats on body parameters, insulin, leptin, milk composition and ultrastructure of the pancreatic islets in dams and offspring

Glucose-dependent insulinotropic peptide (GIP) stimulates Glucagon-like peptide (GLP)-1 from human and mouse pancreatic islets partly via alpha-cell-derived IL-6

QRFP43 and its fragment 26RFa both promote β-cell survival but differently regulate insulin secretion and glucose uptake in pancreatic β-cells and human pancreatic islets

Adhesion G-protein coupled receptors as novel players in islet development

Islet δ-Cells Contribute to the Pathobiology of Atypical Congenital Hyperinsulinism

Adult pancreatic islet progenitor cells exhibit plasticity <i>in vitro</i>

Obestatin improves <em>in vitro</em> generation of novel insulin and glucagon secreting islet-like cell clusters from islet-derived non differentiated cells

Immature β-cells are required for normal islet function and insulin release

Islet Transplantation Plenary 5 (Tuesday 6th May 2014)

Islet of Langerhans in Congenital Hyperinsulinism in Infancy are Disrupted and with Decreased Expression of Collagen (IV) α1 Chain in Basement Membranes

Investigating the role of microRNA-7 in pancreatic islet development

Vegf-A mRNA transfection to improve islet graft revascularization

Impact of number of transplanted human islet equivalents on successful return to normoglycaemia in an NSG diabetic mouse model

Novel mechanisms of islet dysfunction in intrauterine growth restricted rats

10.13. Human islet T cells are highly reactive to preproinsulin in type 1 diabetes

ESE Young Investigator Award

The follicle-stimulating hormone receptor is expressed in human pancreatic islet beta-cells and its activation increases glucose stimulated insulin secretion

Islet adaptations to pregnancy: a role for Urocortin 2

Islet stellate cell isolated from Goto-Kakizaki rats affects β-cell function

Male AKR1D1 (5β-reductase) knockout mice have altered pancreatic islet morphology and hormone secretion

Male 5-beta reductase knockout mice have altered pancreatic islet morphology and hormone secretion

Factors Impacting Survival Outcomes of Islet Cell Carcinoma

A distinct population of islet cells defines diffuse congenital hyperinsulinism in infancy but not other forms of the disease

A Distinct Population of Islet Cells Defines Diffuse Congenital Hyperinsulinism in Infancy but not Other Forms of the Disease

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularization

Statin modulation of growth factors in piglets with metabolic syndrome

Non-islet cell tumor hypoglycemia

Effects of ghrelin treatment to promote proliferation of pancreatic islet in BB rats

Islet mitogens – role in the maintenance of β-cell mass

Liraglutide potently protects against streptozotocin-induced acute islet injury by inhibiting HMGB1 release

Intermittent fasting for three months decreases pancreatic islet mass and increases insulin resistance in Wistar rats

Pancreatic islet protective effect of vanadium in streptozotocin-induced diabetic rats, histological, immunohistochemical and ultrastructural study

Pancreatic islet protective effect of vanadium in streptozotocin-induced diabetic rats, histological, immunohistochemical and ultrastructural study

Circulating ghrelin and leptin concentrations in metabolic disorders of obese and lean piglets

Obestatin and ghrelin inhibit apoptosis of human pancreatic islet endothelial cells in high glucose culture

Factors associated with islet yield and insulin independence after total pancreatectomy and islet cell autotransplantation in patients with chronic pancreatitis utilising off-site islet isolation: Cleveland Clinic experience

Expression of ghrelin and its receptor genes is tissue specific in streptozotocin treated piglets

A paracrine role for 11β-hydroxysteroid dehydrogenase type 1 and glucocorticoids in the murine pancreatic islet

2.14. Gestational diabetes adversely affects pancreatic islet architecture and function in the male rat offspring

A Novel cause of non-islet cell tumour hypoglycaemia

A Novel cause of non-islet cell tumour hypoglycaemia

A role for kisspeptin in long-term islet function in females

A case of non-islet cell tumour hypoglycaemia

A case of non islet cell tumour hypoglycaemia

Liver specific microparticles to improve islet transplantation outcomes in Type 1 diabetes

A Case of Latent Autoimmune Diabetes of Youth Initially Negative for Islet Autoantibodies

Protective effects of <em>Swietenia macrophylla</em> King (seed & endocarp) aqueous-methanolic extract on pancreatic islet histology in streptozotocin-induced diabetic rats

Islet amyloid polypeptide (IAPP) accumulates in lysosomes of human beta-cells by crinophagy but does not form fibrils

Pregnancy induced pancreatic islet expansion is compromised by consumption of cafeteria diet

8.16. Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation

Increased Islet Cell Neogenesis and Endocrine Cell Differentiation in Congenital Hyperinsulinism in Infancy

10.6. Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany

Atypical forms of congenital hyperinsulinism are associated with increased expression of the transcription factor NKX2.2 and increased numbers of somatostain secreting cells

10.7. Circulating metabolites in progression to islet autoimmunity and type 1 diabetes

Evolution of macro-angiopathy 5-years after islet transplantation (IT) in type 1 diabetes

8.9. Elevations in blood glucose before and after the appearance of islet autoantibodies in children

Relationship between Insulin and somatostatin secretory response to Glucagon-like peptide-1 (GLP-1) and glucose concentration in perifused rat pancreatic islet cells

2-Oxoglutaric acid protects against side effects of maximal therapeutic doses of dexamethasone in piglets skeleton

Islet cell proliferation is inappropriately maintained in the pancreas of children with congenital hyperinsulinism in infancy

IGF2 related non-islet cell tumour hypoglycaemia in a patient with hepatic sarcoma

Non islet cell tumour hypoglycaemia resistant to medical treatment

Spontaneous differentiation of mouse embryonic stem cells into an islet phenotype

Spontaneous differentiation of mouse embryonic stem cells into an islet phenotype

Using photo-pharmacology to reveal the importance of the islet beta cell network

Influence of genotype on the endocrine and metabolic control of uncoupling protein (UCP)-2 during the first week of life in neonatal piglets

Non-islet cell tumour hypoglycaemia in a patient with type 1 diabetes mellitus

10.14. Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany

Childhood Thyroid Autoimmunity and Relation to Islet Autoantibodies in Children at Risk for Type 1 Diabetes

Non islet cell tumour hypoglycaemia: management strategies for a rare and challenging condition

Non- islet cell tumour hypoglycaemia associated with ovarian carcinoma

Recurrent hypoglycaemia: an unusual association of islet cell hyperplasia and coeliac disease

15.6. A hormone complex of FABP4 and nucleoside kinases regulates islet function

Continuous glucose monitoring systems and the improvement in hypoglycaemic awareness post-islet transplantation: a single-centre cohort study

Enhanced islet cell neogenesis and endocrine cell differentiation are pathognomonic with congenital hyperinsulinism in infancy

A rare case: non-islet cell tumor hypoglycemia with adrenal insufficiency

Utilising combined treatment modalities in non-islet cell tumour hypoglycaemia (NICTH)

Role of insulin therapy in weight gain: lessons from islet transplantation in type1 diabetes

Anti-islet cell antibodies in a sample of Egyptian females with gestational diabetes and its relation to development of type 1 diabetes mellitus

HOMA-IR and HOMA-islet indices in the evaluation of different carbohydrate metabolism disorders during glucocorticoid therapy

Improvement or stabilization of retinopathy and visual acuity after islet transplantation: a 5-year prospective study

10.4. Extended family history of type 1 diabetes in HLA-predisposed children with and without islet autoantibodies

Fat mass impact of sirolimus after clinical islet transplantation, a case control study

Rat bone marrow mesenchymal stem cells transdifferentiate into islet-secreting cells in vitro

Rat bone marrow mesenchymal stem cells transdifferentiate into islet-secreting cells in vitro

Socioeconomic Factors, Treatment Modality, and Survival in Islet Cell Carcinoma: A National Cancer Database Analysis

Effects of maternal administration of β-hydroxy-β-methylbutyrate on humerus properties in newborn piglets

Title: investigating molecular mimicry between SARS-CoV-2 antigens and pancreatic islet antigens in type 1 diabetes pathogenesis using near-sequence similarity

Obesity-induced changes in hepatocyte and skeletal myocyte expression of mRNAs encoding islet GPCR peptide ligands

Pregnancy following islet cell transplantation in a woman with type 1 diabetes and autoimmune Addisons disease

Total pancreatectomy and pancreatic islet autotransplantation in patient with intractable pain caused by chronic pancreatitis

Non-islet cell tumour hypoglycaemia (NICTH) caused by an intrathoracic tumour and responding well to glucocorticoid therapy

Function and composition of pancreatic islet cell implants in omentum of type 1 diabetes patients

Mesenchymal stem cells-derived microvesicles modulate cellular immune response to islet antigen GAD in type 1 diabetes.

A rare case of steroid responsive non-islet cell tumour hypoglycemia (NICTH) secondary to metastatic haemangiopericytoma

Effects of the prenatal environment on haematological and skeletal muscle parameters in one-week-old piglets: a role for glucocorticoids?

2.15. Childhood height growth rate association with the risk of islet autoimmunity and development of type 1 diabetes

Severe hypothyroidism causing acute ileus and polyserositis

Hypoglycemia due to non islet cell tumor in a non-diabetic patient- a case report

Relation between glucose daily profile (CGMS) and graft function after islet transplantation for type 1 diabetes mellitus

New onset diabetes – frequency of DKA and positive islet autoantibodies at Varna’s diabetes center

10.5. Association of cereal, gluten, and dietary fiber intake with islet autoimmunity and type 1 diabetes

8.4. Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study

A missense mutation in the islet-enriched transcription factor <em>MAFA</em> leads to familial insulinomatosis and diabetes

Severe refractory non-islet cell tumour hypoglycaemia due to metastatic colorectal carcinoma

Thyroid and Islet Autoantibodies Predict Autoimmune Thyroid Disease Already at Diagnosis of Type 1 Diabetes

Comparison of the Occurrence of Islet Autoantibodies in Siblings of Patients with Type 1 Diabetes Mellitus to Healthy Children

Closure by iptakalim, a cardiovascular K(ATP) channel opener, of rat islet beta-cell K(ATP) channels and its molecular basis

Insulin-mimetic effects of short-term Rapamycin in type 1 diabetic patients prior islet transplantation

Non-islet cell tumour hypoglycaemia in adrenocortical carcinoma responding to combined growth hormone and corticosteroid therapy

A case of non-islet cell tumour hypoglycaemia due to advanced hepatocellular carcinoma secondary to previously undiagnosed chronic HBV-infection

10.8. Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should Lead to testing for MODY: lessons from a 5-year pediatric Swedish National Cohort study

10.9. Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study

Simultaneous islet cell and kidney transplant in a patient with Type 1 Diabetes and End-Stage Renal Failure after Roux-en-Y gastric bypass

The importance of islet antigen-2 and glutamic acid decarboxylase antibodies in proper diagnosis of diabetes mellitus at the age ≥30 and <70 years

Liraglutide restores the endocrine function of islets β-cells and the altered lipid profile in early stages of life induced by food restriction in pregnancy

Detection of anti-islet antibodies in capillary blood by the antibody detection by agglutination-PCR (ADAP) technology is sensitive and suitable for general population screening programs

Perspectives of islet cell transplantations

History of meconium ileus affects bone health and body composition in young patients with cystic fibrosis

Protective Effects of Combined Intervention with Adenovirus Vector Mediated il10 and igf1 Genes on Endogenous Islet β Cells in Nonobese Diabetes Mice with Onset of Type 1 Diabetes Mellitus

Protective Effects of Combined Intervention with Adenovirus Vector Mediated IL-10 and IGF1 Genes on Endogenous Islet β Cells in Nonobese Diabetes Mice with Onset of Type 1 Diabetes Mellitus

Case report: adrenal phaeochromocytoma presenting with ileus, renal vein thrombosis and pulmonary embolism

Non-islet cell tumour hypoglycaemia (NICTH)

Non-islet cell tumour hypoglycaemia (NICTH)

Insulinoma, diabetes and islet cell amyloid polypeptide

Single cell transcriptomics in endocrine system physiology: example from the pancreas

Hyperghrelinaemia, hyperphagia, food hoarding and reduced adiposity in an imprinting centre deletion mouse model of PraderWilli syndrome

Structural study on the effect of maternal diabetes on fetal endocrine pancreas

PZ-TR: a novel human luciferase reporter cell line for assessment of thyroid receptor transcriptional activity

Depression and islet function during pregnancy: Generation of a depressive phenotype using UCMS

State of the art in islet cell therapy: preclinical advances in graft revascularization

Pathway Integration of Pro-Inflammatory Cytokines, 12-Lipoxygenase and NADPH Oxidase in Beta Cell Dysfunction; Protection by Novel Selective 12-Lipoxygenase Inhibitors.

Induced maturity affects normal beta cell function

Induced maturity affects normal beta cell function

Proglucagon processing can be altered to produce GLP-1 in pancreatic alpha cells

Cell and gene therapy for diabetes

Cellcell communication and the regulation of insulin secretion

Exploring the translational potential of the NPY Y4 receptor for treating Type 1 Diabetes

Development of novel human stable reporter cell line for the assessment of PPARγ transcriptional activity

Effect of anthocyanidins on trascriptional activities of steroid and nuclear receptors

Somatostatin-expressing cells contribute to the pathobiology of atypical congenital hyperinsulinism in infancy

Non-invasive quantification of pancreatic islet beta-cell function in people with type 1 diabetes mellitus

Non-Islet Cell Tumour Hypoglycaemia in a patient with recurrent meningeal haemangiopericytoma : A Case Report

Syndromic Patients with Negative Islet Autoantibodies should be Tested for Mongenic Diabetes: Lessons from Patient with <em>Trmt10a</em> Mutation

10.21 Loss of intra-islet heparan sulfate is a highly sensitive marker of T1DM progression in humans

Association between osteocalcin and secretory function of islet beta cells in diabetic pediatric population: a pivotal study

Hypovitaminosis-D and the RAS in type 2 diabetes risk

Stem cells as a treatment option in diabetes

Cell-cell contact enhances insulin secretion from pancreatic beta-cells but not glucagon secretion from alpha-cells

Glucose regulates pancreatic β cell Ca<sup>2+</sup> dynamics and connectivity <em>in vivo</em> in the anterior chamber of the mouse eye

Reduced insulin content and secretory capacity in the adult offspring of rats exposed to a high fat diet in pregnancy

Nanomedicine in clinical diabetes

Pancreatic <em>N</em>-Methyl-<small>D</small>-Aspartate Receptors as Novel Drug Targets for The Treatment of Diabetes Mellitus

2.7. Stem cell based models in congenital hyperinsulinism - perspective on practicalities and possibilities

A rapid method for analysing serum pro-insulin-like growth factor-II (pro-IGF-II) in patients with non-islet cell tumour hypoglycaemia (NICTH)

Hubs in the Pancreas

Beta cell progenitor niche(s) and derivation of such cells from human ES cells

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) prevents cytokine-mediated beta cell dysfunction

Oxytocin modulates olfaction-related behaviour and essential for onset of sexual behaviour in both sexes of mice

Identifying the amino acids which mediates the effect of protein on glucagon release

Unacylated ghrelin: a metabolic hormone

Improved glucose metabolism and altered pancreatic structure in transgenic mice overexpressing betacellulin

Maternally derived pancreatic extracellular vesicle miR-375 contributes to large-for-gestational-age infants in pregnancies complicated by gestational diabetes

Glucose regulates miR-184 via AMP-activated protein kinase (AMPK) in pancreatic β-cells