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Diabetes IGF

Islets Insulin BetaCells Pancreas Glucose Hyperglycemia Hypoglycemia Insulinoma Glucagon IGF Type 1 Type 2
New BSPED rhIGF-1 guidance documents
2024-06-0404Jun2024
IGF1 gene important for tendon growth
2019-09-2020Sep2019
IGF1 gene important for tendon growth
2019-09-2020Sep2019
6th International Congress of the Growth Hormone Research and IGF Society
2012-03-1414Mar2012
ESE welcomes new Affiliated Society
2012-02-1313Feb2012
Postdoctoral Research Scientist: Electrophysiological characterization of Hypothalamic Dopaminergic neurons
2008-02-1111Feb2008
Research Engineer: Development of in vivo imaging techniques with cellular resolution
2008-02-1111Feb2008
Postdoctoral Research Scientist: In vivo functioning of pituitary-scale cell networks
2008-02-1111Feb2008
IGF1 Assays
Date not available
How to manage patients with acromegaly and discordant GH and IGF-I results
Date not available
Control of GH and IGF1 in acromegaly in the UK: responses to medical treatment
Date not available
MicroRNA regulation of the IGF axis
Date not available
Development of a novel mass spectroscopy-based method for determining serum IGF-1 - assessment in a ...
Date not available
IGF-1 receptor and insulin receptor stoichiometry is a critical determinant of nitric oxide bioavail...
Date not available
Dicer-dependent microRNAs regulate IGF-actions in the human placenta
Date not available
Effects of insulin-like growth factor 1 (IGF-1) on early folliculogenesis in polycystic ovaries from...
Date not available
GH/IGF-I and the cardiovascular system
Date not available
Discordant GH and IGF-I results in acromegaly: a headache?
Date not available
Discordant GH and IGF-I results in acromegaly: a headache?
Date not available
Symptomatic hypoglycaemia due to high IGF-2 levels in a patient with adrenocortical carcinoma
Date not available
Paraneoplastic hypoglycaemia secondary to IGF-2 secretion from a metastatic gastrointestinal stromal...
Date not available
A rare heterozygous IGFIvariant causing postnatal growth failure and offering novel insights into IGF-I physiology
Date not available
Acromegaly: Challenges in Managing Post-Treatment Elevated Growth Hormone (GH) /Insulin like Growth Factor-1 (IGF-1) Levels and the Role of Pasireotide
Date not available
A young Acromegalic patient (AIP+) with poor response to SRLs and discordant GH / IGF1
Date not available
HETEROZYGOUS IGF1R MUTATIONS REPRESENT A FREQUENT FINDING IN PATIENTS WITH PRE- AND/OR POSTNATAL PRO...
Date not available
Characterization of IGF-I receptor expression and localization in paediatric gliomas upon diagnosis ...
Date not available
Topicon™ ThermoMatrix™-mediated passive transdermal delivery of insulin-like growth factor 1 (IGF-1)...
Date not available
IGF-I levels, complex formation and igf-bioactivity in growth hormone treated children with Prader-W...
Date not available
Paternally inherited IGF2 mutation results in intrauterine and postnatal growth retardation
Date not available
The complex relationship between the GH/IGF axis and aging and longevity – the interface with diet a...
Date not available
Expression of type 1 insulin-like growth factor receptor (IGF-1R) in liver of obese children with non-alcoholic fatty liver disease (NAFLD)
Date not available
Characteristics of responders and poor-responders to Increlex® therapy – data from children enrolled in the European Increlex® Growth Forum Database (EU-IGFD)
Date not available
Optimal Sampling of IGF-1 During Weekly Administration of a Long Acting Human Growth Hormone (MOD 4023)
Date not available
PAPP-A2 Gene Mutation Effects on Glucose Metabolism and Bone Mineral Density and Response to Therapy with Recombinant Human IGF-I
Date not available
Contribution of GHR and IGFALS mutations to growth hormone resistance – Identification of new variants and impact on the inheritance pattern
Date not available
CG methylation at the IGF1 P2 promoter is a major epigenetic determinant of postnatal, not foetal growth.
Date not available
CG at the methylation IGF1 locus is an epigenetic predictor of GH sensitivity.
Date not available
Type 1 diabetes associated serum Insulin-like growth factor I (IGF-I) reference values in children and adolescents
Date not available
Effects of IGF-1R nuclear localization in glioblastoma cells.
Date not available
A Cross-sectional Study of IGF-I Bioavailability through Childhood and Associations with PAPP-A2, ST...
Date not available
Metabolomic changes in patients with PAPP-A2 deficiency in response to rhIGF1 treatment.
Date not available
Patients with GH Insensitivity and IGF-1 Resistance Harbour Copy Number Variants Causing a Silver-Ru...
Date not available
IGF-I at four months associates to visceral and subcutaneous adipose tissue at 7 years of age.
Date not available
Circulating MKRN3, Kisspeptin and IGF-1 levels in girls during the clinical onset of puberty.
Date not available
The association between IGF-1 levels and nonalcoholic fatty liver disease (NAFLD) in adolescents with type 2 diabetes
Date not available
Peripheral and hypothalamic alterations in the insulin like growth factor IGF system in response to high fat diet induced weight gain
Date not available
IGF-1 serum concentrations and growth in children with congenital leptin deficiency (CLD) before and after replacement therapy with metreleptin
Date not available
Increasing knowledge in IGF1R defects: lessons from 20 new patients.
Date not available
Bioactive IGF-I concentration compared to total IGF-I concentration before and after 1 year of high-dose growth hormone in short children born small for gestational age – North European SGA Study (NESGAS)
Date not available
Inhibition of IGF1R by IGF1R/IR inhibitor OSI906 as a targeted therapy for glioblastoma: in vitro & in vivo studies
Date not available
Pubertal onset in 1572 girls with short, normal and tall stature: associations to height, serum IGF-I and PAPP-A2 genotypes
Date not available
Papp-a2 deficiency induces sex-specific changes in hydroxyapatite-(CaOH) crystallinity and the effects of IGF-1 on bone composition in adult mice
Date not available
Identifying patients with severe primary IGF-1 deficiency: Importance of diagnostic assays
Date not available
Maximising growth: Treating patients with severe primary IGF-1 Deficiency (SPIGFD)
Date not available
GH titration by IGF-I in children born SGA and Turner syndrome
Date not available
Physiological and GH-related IGF-I variations in children affected by Noonan syndrome
Date not available
Are pappalysins and stanniocalcins involved in modifying the bioavailability of IGF-I in children with onset of type 1 diabetes mellitus?
Date not available
Functional analysis of a novel mutation of IGF1R gene in two twins with growth failure. An example of genotype-phenotype heterogeneity.
Date not available
Influence of sirtuin 1 and fibroblast growth factor 21 levels on IGF-1 concentration in children with short stature of different etiology
Date not available
Deconvolution Analysis: GH secretagogue (LUM-201) enhances growth in individuals with moderate idiopathic Pediatric Growth Hormone Deficiency (iPGHD) by enhancing endogenous GH secretion and increasing IGF-1
Date not available
Predicting Average IGF-I Concentration for Once-Weekly Somapacitan in Children with Growth Hormone Deficiency
Date not available
The Effects of Blue Light Exposure on the Epiphyseal Plate and IGF1 - IGFBP3 Expression in Rats
Date not available
First line treatment evaluation in patients with severe primary insulin-like growth factor 1 deficiency (SPIGFD): Data from the Global Increlex® Registry
Date not available
Understanding the molecular basis of short stature in Fanconi Anemia: Impact of pappalysins and stanniocalcins on IGF-I bioavailability
Date not available
Use of iSYS-IDS IGF1-Assay Normative Data as a STANDARD in the Diagnosis of Pediatric Growth Hormone Deficiency
Date not available
Growth, IGF-1 and IGFBP-3 Responses to Oral LUM-201 in OraGrowtH210 and OraGrowtH212 Trials in Pediatric Growth Hormone Deficiency (PGHD) over 12 to 24 Months on Treatment
Date not available
Association of whole blood amino acid and acylcarnitine metabolome with anthropometry and IGF1 serum levels in healthy children and adolescents
Date not available
Amount and Pattern Of Pulsatile GH Secretion Induced By The Oral Growth Hormone Secretagogue LUM-201 Is Related To Growth And IGF-1 Responses In Moderate Pediatric Growth Hormone Deficiency (PGHD)
Date not available
Recombinant human Insulin-like growth factor-1 (rhIGF-1) therapy: a 15-year experience in a tertiary...
Date not available
Recombinant human Insulin-like growth factor-1 (rhIGF-1) therapy: a 15-year experience in a tertiary...
Date not available
Patients with short stature and GH/IGF-1 Insensitivity harbour Copy Number Variants causing a Silver...
Date not available
Phenotypic spectrum and response to recombinant human IGF1(rhIGF1) therapy in patients with homozygo...
Date not available
Lysinuric Protein Intolerance: A Cause of Secondary IGF-I Deficiency With Raised Growth Hormone Leve...
Date not available
Genetic characterisation of children with short stature and GH or IGF-1 insensitivity by single gene...
Date not available
FGF21 causes GH resistance in human chondrocytes through activation of SOCS2 and inhibition of IGF1 ...
Date not available
Growth, GH-IGF-I Status and Response to r-hGH Therapy in 3-M Syndrome, Related to Mutation Status
Date not available
Short Term Effects of Recombinant IGF-I therapy in children with Laron’s Syndrome.
Date not available
A selective effect of IGFBP-3 on brain volumes in healthy children
Date not available
A rare case of short stature with high total Insulin Like Growth Factor 1 (IGF-1) and a novel pregnancy-associated plasma protein A2 (PAPPA2) gene mutation
Date not available
Analysis of signal transduction in mice overexpressing mutant versus intact IGFBP-2 identifies a ple...
Date not available
Maternal distress associates with placental genes regulating fetal glucocorticoid exposure and IGF2:...
Date not available
Combined GH and IGF-1 treatment
Date not available
Problems with GH and IGF-1 assays: progress?
Date not available
Relationship between oestrogen and IGF system in neuroprotection
Date not available
The combination of GH/IGF-I makes the difference!
Date not available
Effects of pregnancy on GH/IGF-1 concentrations in acromegalic women.
Date not available
ROLE OF IGF SYSTEM ON THE REGULATION OF OSTEOBLAST AROMATASE ACTIVITY IN VITRO
Date not available
Dietary restriction and altered insulin/Igf1 signalling: conserved mechanisms regulating lifespan in...
Date not available
Specifying the cellular responses to IGF signalling by IGF binding proteins: New lessons from the ze...
Date not available
Expression of IGF-I & IGF-IR in Tamoxifen Sensitive and Tamoxifen Resistant Breast Cancer
Date not available
Calcium carbonate supplementation of pregnant rural Gambian mothers alters offspring IGF-1 at age 7....
Date not available
Treatment with recombinant murine Pappa2, GH or IGF-1 modifies hepatic energy metabolism in a mouse model of Pappa2 deficiency
Date not available
Predicted Ratio of IGF-1 Observations and Differences in IGF-1 SDS Observations to 96-hour Values Over the Dosing Interval in Pediatric pGHD Patients Receiving Somatrogon
Date not available
Overexpression of Brachyury and IGF1R in Thyroid Papillary Carcinoma cells: different phenotypes and asocciation with pediatric Thyroid Nodular Pathology
Date not available
In vitro funcional characterizationof two novel missense IGF1 variants
Date not available
Mice with placental junctional zone Igf2 deletion fail to metabolically adapt during pregnancy
Date not available
Sex-specific placental IGF-system adaptations to maternal exercise in growth restricted mothers
Date not available
IGFBP-1 as a predictor of hip fractures
Date not available
Telomerase promotes osteoblast differentiation by modulating IGF-signaling pathway
Date not available
IGF-1 regulates MC-3T3 and human primary osteoblast to osteocyte differentiation in 3D culture
Date not available
Resource not read: Query You and Your Hormones
Prenatal caffeine and glucocorticoid−IGF1 axis-mediated testicular dysplasia
2019-09-1919Sep2019
The latest from your society journals
2018-12-1414Dec2018
HORMONES FOR BONE HEALTH IN FUNCTIONAL HYPOTHALAMIC AMENORRHOEA
2024-03-2727Mar2024
An interview with…Colin Farquharson, new Co-Editor-in-Chief of two society journals
2018-06-0606Jun2018
Mechanisms driving adrenocortical carcinoma metastasis
2018-02-2828Feb2018
GH REPLACEMENT FOR TRAUMATIC BRAIN INJURY AND SUBARACHNOID HAEMORRHAGE
2024-09-1717Sep2024
An unusual cause of gynaecomastia in a male
2019-09-1919Sep2019
075.pdf
2018-04-1111Apr2018
Exercise and endocrinology in advanced age with a focus on testosterone
2020-03-1212Mar2020
Iodine status: determination and optimisation in the UK and beyond
2018-09-1919Sep2018
ASSISTED CONCEPTION AND AGEING
2023-03-1515Mar2023
Endocrine cancer progression and metastases
2021-09-2222Sep2021
Reproductive medicine: time is of the essence
2019-12-1818Dec2019
JEKYLL AND HYDE: LESSONS FROM SEVERE INSULIN RESISTANCE
2023-12-1515Dec2023
Let’s talk: genetic testing
2019-06-1111Jun2019
106.pdf
2018-04-1111Apr2018
Genomics in mainstream endocrinology
2016-10-0606Oct2016
ION CHANNELS, SPERM AND MALE INFERTILITY
2022-03-1616Mar2022
ADVANCING SCIENTIFIC DISCOVERY WITH EARLY CAREER GRANTS FOR YOUR RESEARCH PROJECTS
2022-09-1616Sep2022
071.pdf
2018-04-1111Apr2018
067.pdf
2018-04-1111Apr2018
070.pdf
2018-04-1111Apr2018
PUBLIC ENGAGEMENT THROUGH PLACENTA-THEMED PRINTING
2022-12-1414Dec2022
063.pdf
2018-04-1111Apr2018
086.pdf
2018-04-1111Apr2018
059.pdf
2018-04-1111Apr2018
082.pdf
2018-04-1111Apr2018
080.pdf
2018-04-1111Apr2018
Induction of spermatogenesis in men with gonadotrophin deficiency
2018-06-0606Jun2018
Less than full time working: the benefits and challenges
2019-09-1919Sep2019
090.pdf
2018-04-1111Apr2018
Endocrinologist 129 Web
2023-11-0101Nov2023
102.pdf
2018-04-1111Apr2018
Endocrinologist 133 Web
2023-11-0101Nov2023
The Endocrinologist Autumn 14 -website.pdf
2018-04-1111Apr2018
083.pdf
2018-04-1111Apr2018
The Endocrinologist 117 Web.pdf
2018-04-1111Apr2018
089.pdf
2018-04-1111Apr2018
079.pdf
2018-04-1111Apr2018
092.pdf
2018-04-1111Apr2018
ScreenSummerEndoComplete.pdf
2018-04-1111Apr2018
068.pdf
2018-04-1111Apr2018
081.pdf
2018-04-1111Apr2018
Endocrinologist 151 Final
2024-03-2727Mar2024
104.pdf
2018-04-1111Apr2018
074.pdf
2018-04-1111Apr2018
061.pdf
2018-04-1111Apr2018
108.pdf
2018-04-1111Apr2018
072.pdf
2018-04-1111Apr2018
107.pdf
2018-04-1111Apr2018
069.pdf
2018-04-1111Apr2018
073.pdf
2018-04-1111Apr2018
The Endocrinologist 114 Web.pdf
2018-04-1111Apr2018
Endocrinologist 128 Web Updated
2023-11-0101Nov2023
093.pdf
2018-04-1111Apr2018
Endocrinologist 153 Web Version
2024-10-1515Oct2024
100.pdf
2018-04-1111Apr2018
099.pdf
2018-04-1111Apr2018
120.pdf
2018-04-1111Apr2018
062.pdf
2018-04-1111Apr2018
Endocrinologist 147 Web
2023-03-0808Mar2023
Endocrinologist 134 Web Updated
2023-11-0101Nov2023
088.pdf
2018-04-1111Apr2018
The Endocrinologist 127 Web.pdf
2018-04-1111Apr2018
064.pdf
2018-04-1111Apr2018
Endocrinologist 135 Web
2023-11-0101Nov2023
058.pdf
2018-04-1111Apr2018
105.pdf
2018-04-1111Apr2018
084.pdf
2018-04-1111Apr2018
Endocrinologist 130 Web
2023-11-0101Nov2023
109.pdf
2018-04-1111Apr2018
091.pdf
2018-04-1111Apr2018
066.pdf
2018-04-1111Apr2018
060.pdf
2018-04-1111Apr2018
085.pdf
2018-04-1111Apr2018
076.pdf
2018-04-1111Apr2018
Endocrinologist 126
2023-11-0101Nov2023
095.pdf
2018-04-1111Apr2018
Endocrinologist 143 Web
2023-11-0101Nov2023
087.pdf
2018-04-1111Apr2018
The Endocrinologist 116 Web FINAL v2.pdf
2018-04-1111Apr2018
094.pdf
2018-04-1111Apr2018
The Endocrinologist 132.pdf
2019-06-1212Jun2019
Endocrinologist 150 Web
2023-12-0707Dec2023
056.pdf
2018-04-1111Apr2018
096.pdf
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110.pdf
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Endocrinologist 127 Web
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103.pdf
2018-04-1111Apr2018
Endocrinologist 141 Web
2023-11-0101Nov2023
Endocrinologist 145 Web
2022-09-0505Sep2022
Endocrinologist 146 Web
2022-12-0707Dec2022
097.pdf
2018-04-1111Apr2018
Endocrinologist 125 Web
2023-11-0101Nov2023
The Endocrinologist spring14 web version FINAL.pdf
2018-04-1111Apr2018
VEGF, FGF and HGF in differentiated thyroid cancer
Date not available
IGF-I and neuroprotection
2009-01-0404Jan2009
The Diagnostic Value of IGF-II, IGF-I and IGFBP-3 in Silver–Russell Syndrome
Date not available
IGF-independent actions of IGFBPs
Date not available
MicroRNA regulation of the IGF axis
2012-01-0303Jan2012
Normal IGF-bioactivity and low free IGF-I in patients with Prader-Willi syndrome with high total serum IGF-I: immunoreactive IGF-I concentrations poorly reflect IGF bio-activity and bio-availability
2019-01-0505Jan2019
Normal IGF-Bioactivity and Low Free IGF-I in Patients with Prader-Willi Syndrome with High Total Serum IGF-I: Immunoreactive IGF-I Concentration Poorly Reflects IGF Bio-Activity and Bio-Availability.
Date not available
Genes for IGF2 and related IGF binding proteins are associated with longitudinal trends in BMI
2013-01-0303Jan2013
A rare heterozygous <em>IGFI</em> variant impairing IGF-I cleavage and causing postnatal growth failure: a novel disease mechanism offering insights into IGF-I physiology
Date not available
A rare heterozygous <em>IGFI</em> variant causing postnatal growth failure and offering novel insights into IGF-I physiology
2021-11-0606Nov2021
Significance of IGF-I Generation Test in Diagnosing Primary and Non-Primary IGF-I Deficiency &#150; Clinical Considerations
Date not available
The combination of GH/IGF-I makes the difference!
2008-01-0505Jan2008
A rare heterozygous <em>IGFI</em> variant causing impaired IGF-I cleavage and postnatal growth failure: a novel disease mechanism with insights into IGF-I physiology
Date not available
The differential influence of specific plant lectins on insulin and IGFs binding to solubilised placental membrane IGF and insulin receptors
2006-04-1212Apr2006
GH/IGF-I and the cardiovascular system
2007-01-0303Jan2007
IGF paracrine and autocrine interactions between conceptus and oviduct
2019-05-0404May2019
Insulin-like growth factor-1 (IGF-I) assays
2018-02-1111Feb2018
Quantum dot labelled IGF-I: a novel technique to study IGF-signal transduction in the human placenta
2009-01-0303Jan2009
Lack of influence of an IGF-I gene polymorphism on circulating IGF-I levels in severely GHD adults
2006-04-1212Apr2006
PTTG promotes mitogenic mechanisms in thyroid cells through autocrine pathways of interaction with TGF-&#945;, EGF and IGF1
Date not available
Expression of the IGF system in the involuting bovine uterus
2007-01-0303Jan2007
How useful is IGF-I in adults with GH deficiency?
2005-01-0303Jan2005
IGF, somatotropic plasticity and mammalian lifespan
2009-01-0404Jan2009
Expression of IGF-I &#38; IGF-IR in tamoxifen sensitive and tamoxifen resistant breast cancer
2006-04-1212Apr2006
The clinical values of IGF1 and IGF-binding protein-3 levels in blood and thyroid nodules
Date not available
The IGF system during acute hypoxia in children
2009-01-1111Jan2009
The role of IGFBPs in the tissue-specific actions of IGFs
2011-01-0404Jan2011
Dicer-dependant microRNAs regulate IGF-actions in the human placenta
Date not available
Longitudinal association of the anti-inflammatory serum marker GDF-15 with serum IgA and IgG in apparently healthy children
2021-06-0909Jun2021
Can adults with severe growth hormone deficiency (AsGHD) and a low IGF-I be distinguished from those with a normal IGF-I?
2006-04-1212Apr2006
Sexual Dimorphism of IGF1 and IGF2 Expression in the Neonatal Rat Brain
Date not available
Expression of IGF/mTOR pathway components in human pheochromocytomas and <em>in vitro</em> inhibition of PC12 rat pheochromocytoma cell growth by mTOR inhibitors alone and in combination with the dual IGFI-R/INS-R antagonist OSI-906
Date not available
Linear growth and response to GH therapy in children with GHD with normal IGF-I versus those with normal GH secretion associated with low IGFI at presentation.
2021-06-0909Jun2021
IGF1 Levels, Complex Formation, and IGF-Bioactivity in GH-Treated Children with Prader&#150;Willi Syndrome
Date not available
Concordance between GH determination and IGF-I in acromegaly using two IGF-I methods
2006-04-1212Apr2006
High Protein Nutritional Supplementation Increases Serum IGF-I Concentrations in Short Children with Low IGF-I
Date not available
IGF-independent acceleration of myogenesis by IGFBP-5: modulation of cell survival and differentiation signalling pathways
2004-01-1111Jan2004
IGF-independent acceleration of myogenesis by IGFBP-5: modulation of cell survival and differentiation signalling pathways
2004-01-1111Jan2004
4.3. IGF2 Mutations
Date not available
Specifying the cellular responses to IGF signalling by IGF binding proteins: new lessons from the zebrafish model
2006-04-1212Apr2006
INVESTIGATION OF THE MECHANISM OF IGF-INDEPENDENT ACTIONS OF IGFBP-4
2001-01-1111Jan2001
Possible predictive value of IGF-II mRNA expression in breast cancer (BC)
2006-04-1212Apr2006
Microarray analysis of IGF-I mRNA positive and negative breast tumours
2004-01-0303Jan2004
The IGF system shows changes in the follicular fluid of women with PCOS.
Date not available
Mechano growth factor (MGF) expression increased in secondary compared to primary foci in well neuroendocrine neoplasms
Date not available
Polycystic ovary syndrome and insulin-like growth factor (IGF) system.
2018-08-0505Aug2018
It is not Just the Growth Hormone-IGF-I Axis
Date not available
GH/IGF-I axis and haematological alterations in anorexia nervosa
2006-04-1212Apr2006
IGF-I prevents deoxycholic acid-induced apoptosis in HT29 colorectal cells
2002-01-1111Jan2002
Telomerase promotes osteoblast differentiation by modulating IGF-signaling pathway
2014-01-0505Jan2014
How to manage patients with acromegaly and discordant GH and IGF-I results
Date not available
Role of IGF system on the regulation of osteoblast aromatase activity in vitro
Date not available
The effects of surgery and tamoxifen on serum IGF-I and IGFBP3 levels in breast cancer
2004-01-0303Jan2004
IGF-I and IGFBP-3 mRNA expression in tamoxifen-resistant, recurrent breast cancers
2004-01-0303Jan2004
IGF-I and IGFBP-3 mRNA expression in tamoxifen-resistant, recurrent breast cancers
2004-01-0303Jan2004
Paracrine IGF-I expression in the colon is associated with elevations of tumourigenic genes
2002-01-1111Jan2002
Auxological and IGF system parameters in African in comparison with western countries normal children
Date not available
IGFBP-5 regulates IGF-I mediated signaling and survival in the mouse mammary gland
2002-01-0303Jan2002
Growth hormone receptor and type 1 IGF receptor in human somatotroph tumours
2002-01-0303Jan2002
Abnormalities in growth and in the IGF system can be associated to permanent chronic inflammatory process in HIV-infected children independently of clinical control
2013-01-0404Jan2013
Effect of cholesterol depletion on IGF-induced cell survival: the role of caveolar and non-caveolar domains
2005-01-0303Jan2005
Crosstalk between IGF signalling and cadherin-mediated cell adhesion promotes myogenic differentiation
2003-01-1111Jan2003
IgM thyroglobulin autoantibodies are detectable in serum of patients with subacute thyroiditis
2018-08-0505Aug2018
Maternal and cord blood serum IGF1 IGF binding protein-3, in asymmetrically small for gestational age neonates
2014-01-0303Jan2014
The myotoxic growth factor: a novel role of IGF-I in skeletal myoblasts?
2008-01-0404Jan2008
IGF-I modulates HIF-1&#945; and HIF-2 &#945; in Kaposi Sarcoma
2006-04-1212Apr2006
Localisation of type I IGF receptor and androgen receptor proeins in small preantral follicles of human ovaries
2002-01-1111Jan2002
2.12. Pappalysins and stanniocalcins and their relationship with the peripheral IGF axis in newborns and during development
2023-08-0909Aug2023
IGF-mediated cell turnover in the human placenta is positively regulated by the protein tyrosine phosphatase, SHP-2
2008-01-0404Jan2008
Impact of new standardization on IGF-I assay IMMULITE 2000
2017-03-0505Mar2017
IGF-I inhibits COX-2 function in primary colonic biopsies of patients with acromegaly
2003-01-0303Jan2003
Bone Marrow Adiposity and IGF System in Obese Children and Adolescents
Date not available
Type 1 Diabetes Associated Serum Insulin-Like Growth Factor I (IGF-I) Reference Values in Children and Adolescents
Date not available
IGFBP-3 has both IGF-dependent and &#150;independent effects on cytotrophoblast proliferation in the human placenta
2007-01-0303Jan2007
Long term culture of MCF-7 breast cancer cells with siRNA to the IGF-I receptor causes continued transcriptional silencing of the IGF-I receptor and decreased cell proliferation
2005-01-0303Jan2005
The severity of obstructive sleep apnoea does not influence ambient IGF-I levels
Date not available
The severity of obstructive sleep apnoea does not influence ambient IGF-I levels
Date not available
The effects of ghrelin on IGF-I expression in normal and malignant breast tissue explants
2004-01-0303Jan2004
Predicting Average IGF-I Concentration for Once-Weekly Somapacitan in Children with Growth Hormone Deficiency
Date not available
Bioactive IGF-I Concentration Compared to Total IGF-I Concentration Before and After 1 Year of High-Dose Growth Hormone in Short Children Born Small for Gestational Age - North European SGA Study (NESGAS)
Date not available
IGF acts through the IGF1R mediated PI3K pathway in first trimester human placenta to rescue cytotrophoblasts from apoptosis
2006-01-1010Jan2006
Role of IGF(CA)19 gene polymorphism in the clinical presentation of acromegaly
2013-01-0404Jan2013
Birth Length, Weight and Head Circumference of Neonates with IGF-I Receptor Mutations
Date not available
Intermittent high glucose concentrations reduce neuronal precursor proliferation by altering the IGF system: the involvement of the neuroprotective factor seladin-1
2008-01-0505Jan2008
Inhibition of IGF-II signal transduction improves chemosensitivity in human adrenocortical cancer cells
2006-04-1212Apr2006
The Expression of IGF Type 1 Receptor is Increased in Obese Children
Date not available
Interaction of androgen with IGF signalling in preantral follicle development in the mouse ovary
2014-01-0303Jan2014
Transcriptional silencing of the IGF-I receptor inhibits proliferation of MCF-7 breast cancer cells
2004-01-0303Jan2004
Insulin decreases IGF-I bioactivity in patients with impaired glucose tolerance and in healthy subjects
Date not available
Expression of IGF/mTOR pathway components in human pheochromocytomas and <i>in vitro</i> inhibition of PC12 rat pheochromocytoma cell growth by mTOR inhibitors
2011-01-0404Jan2011
Differential regulation of the neurotrophins, NGF and BDNF, and their receptors in the myometrium of women affected by adenomyosis
2011-01-0404Jan2011
Long-term unidentified complication of IGF-I treatment: Pulmoner hypertension
Date not available
Improved quality of life (QOL) with normalisation of IGF-I in patients with acromegaly
2004-01-0303Jan2004
Glucose-suppressed GH levels compared with IGF-I levels in patients with acromegaly
2006-04-1212Apr2006
Characteristics, Effectiveness and Safety Data from Clinically Relevant Subgroups of Patients with Severeprimary IGF-I Deficiency (SPIGFD): Results from the European Increlex<sup>&#174;</sup> Growth Forum Database (EU-IGFD) Registry
Date not available
Understanding the molecular basis of short stature in Fanconi Anemia: Impact of pappalysins and stanniocalcins on IGF-I bioavailability
Date not available
TRANSFORMING GROWTH FACTOR BETA (TGF) and INSULIN LIKE GROWTH FACTOR (IGF) MEDIATED RESPONSES, TO SERIAL CONCENTRATIONS OF NICOTINE, USING ANDROGEN BIOMARKERS IN HUMAN GINGIVAL FIBROBLASTS
2003-01-1111Jan2003
Interactions of vitamin D analogues with downstream effectors of insulin-like growth factor 1 (IGF-I) signalling
2002-01-0303Jan2002
Does IGF influence the prognosis 10 months after myocardial infarction?
2015-01-0505Jan2015
IGF(CA)19 and IGFBP-3-202A/C gene polymorphism in patients with acromegaly
2010-01-0404Jan2010
Spurious hypoglycaemia caused by an IgM paraprotein
Date not available
2.5. Tracking and cumulative lifetime exposure to IGF-I in 6459 healthy individuals and in SGA children treated with GH
2023-08-0909Aug2023
Macronutrient composition has sex specific effects on the GH-IGF-I axis
Date not available
Lysinuric protein intolerance associated with vertebral fractures and IGF-I deficiency
2017-11-0707Nov2017
IGF-I STIMULATES EARLY FOLLICULAR DEVELOPMENT IN CULTURED HUMAN OVARIAN TISSUE
2003-01-1111Jan2003
Activation of selective human sperm functions by EGF and TGF-&#946;3 is mediated by an ERK-depended mechanism
2012-01-0505Jan2012
Quality of Life (QoL) and IGF-I Status in Adults with Severe GHD
Date not available
4.9. Low IGF-I bioavailability impairs growth and glucose metabolism in a mouse model of human PAPPA2 p.Ala1033Val mutation
2019-12-0909Dec2019
Peripheral and Hypothalamic Alterations in the Insulin-like Growth Factor (IGF) System in Response to High Fat Diet-induced Weight Gain
Date not available
Somapacitan expected to provide IGF-I levels suitable for once-weekly dosing in children
2017-03-0505Mar2017
Prolactin deficiency is independently associated with reduced IGF-I status in severely GHD adults
2006-04-1212Apr2006
Variability in IGF-I assay performance undermines its contribution to the management of GH axis disorders
2004-01-1111Jan2004
The influence of a GH receptor antagonist (GHRA) on the relationship between GH and IGF-I in adults with severe growth hormone deficiency (AGHD)
2006-04-1212Apr2006
Reduction in pappalysin and stanniocalcin levels explain the decrease in IGF-I bioavailability in anorexia nervosa
2021-06-0909Jun2021
Growth hormone (GH) treatment of children with idiopathic short children (ISS) with normal insulin-like growth factor-1 (IGF-1) versus those with low IGF-I at diagnosis.
2021-06-0909Jun2021
IGFBP3 and IGFBP2 negatively and positively modulate IGFs autocrine effect in lung cancer cell lines
2009-01-0404Jan2009
A rapid method for analysing serum pro-insulin-like growth factor-II (pro-IGF-II) in patients with non-islet cell tumour hypoglycaemia (NICTH)
2003-01-0303Jan2003
Relationships of IGF-I and its binding proteins to cardiac, large and small vessel structure and function in premenopausal women
2008-01-0404Jan2008
IGF II protein expression in breast cancer. Relationship with the most important predictive parameters in breast malignancy
2006-04-1212Apr2006
EFFECT OF MATERNAL NUTRIENT RESTRICTION DURING LATE-GESTATION ON THE HEPATIC INSULIN-LIKE GROWTH FACTOR (IGF) SYSTEM IN NEONATAL SHEEP
2003-01-1111Jan2003
IGF-I reverses dexamethasone induced growth retardation in mouse embryonic metatarsal cultures
2003-01-0303Jan2003
Expression of IGF-I in normal and malignant breast tissue and its association with tumour size
2003-01-0303Jan2003
Monitoring of weekly IGF-I levels during long-acting growth hormone therapy with somapacitan
Date not available
Severe IGF-I Deficiency in Children with Normal Growth Hormone (GH) Secretion and Excluded GH Insensitivity &#150; is it Really Idiopathic Short Stature?
Date not available
IGF binding protein-2 is associated with all-cause and cardiovascular mortality in type 2 diabetes
2013-01-0303Jan2013
Serum IGF-I levels and correlation with functional activity in the elderly
2002-01-0303Jan2002
Low insulin-like growth factor (IGF) I, IGF binding protein-3 and acid labile subunit (ALS) levels in young ischemic stroke: a prospective case-control study
2008-01-0505Jan2008
A Cross-Sectional Study of IGF-I Bioavailability Through Childhood and Associations with PAPP-A2, STC2 and Anthropometric Data
Date not available
Insulin like growth factor-I (IGF-I) levels and metabolic parameters in a population of obese children and adolescents
2012-01-0505Jan2012
The role of the growth hormone-insulin-like growth factor-I (GH-IGF-I) axis in the aetiology of male idiopathic osteoporosis
2004-01-0303Jan2004
The IGF system influences prevalence of the metabolic syndrome in a population with high rates of cardiovascular disease
2004-01-0303Jan2004
Dietary intake and the IGF-system: a study in two related populations with a markedly different dietary intake
2004-01-0303Jan2004
Anthropometry and Glucose Homeostasis in a Patient with Donohue Syndrome (Homozygous Insulin Receptor Mutation): Effect of Continuous s.c. rIGF-I Therapy
Date not available
The role of IGFs and the Sertoli cell in driving &#145;maleness'
2013-01-0303Jan2013
IGF-I is not suppressed in adolescents submitted to resistance training and can be a marker of training status
2018-08-0505Aug2018
Dynamic Changes in Growth and IGF-I During the First Year of Life; A Longitudinal Study of 233 healthy Danish Infants
2021-06-0909Jun2021
Controversies in the spectrum of GH-IGF-I axis disorders requiring replacement therapy
Date not available
GH/IGF-I impact hepatic lipid accumulation in non-acromegalic individuals with and without non-alcoholic fatty liver disease
2022-07-0505Jul2022
Normal age-dependent values of serum insulin growth factor (IGF)&#150;I: results from a healthy Italian population
Date not available
Somatostatin Abrogates GH-Induced Hepatocyte IGF-I Transcription by Inhibiting STAT5b Phosphorylation &amp; Nuclear Translocation
2004-01-1111Jan2004
The effect of insulin-like growth factor-I (IGF-I) on initiation of human follicle growth in vitro
2003-01-0303Jan2003
Insulin, IGF-II and a low-affinity insulin analog differentially regulate insulin receptor isoform A trafficking and induce a different balance of metabolic and mitogenic effects
2012-01-0505Jan2012
IDF but not ATPIII predicts the presence of ischaemic heart disease
2007-01-0303Jan2007
Circulating IGF-II concentration is associated with longitudinal increase in high density lipoprotein cholesterol in Type 2 diabetes
2012-01-0303Jan2012
Polymorphisms of the IGFBP3 gene influence circulating IGF-II concentration in type 2 diabetes
2012-01-0303Jan2012
Alteration to PGF and IGF-1, signalled the adverse growth of the foetus and placenta in a genistein exposed pregnancy in experimental rats
2018-02-1111Feb2018
Somapacitan dose&#8211;IGF-I&#8211;response and impact of starting dose levels in adults with growth hormone deficiency &#8211; a model-based analysis
Date not available
Evidence for a role of the Type 1 IGF receptor in early follicular development in cultured human ovarian tissue
2004-01-1111Jan2004
Evidence for a role of the Type 1 IGF receptor in early follicular development in cultured human ovarian tissue
2004-01-1111Jan2004
Effects of zinc, magnesium and vitamin B6 (ZMA) supplementation on serum IGF-I, IGFBP-3 and Testosterone concentrations in young athletes
2018-08-0505Aug2018
IGF-I at Four Months Associates to Visceral and Subcutaneous Adipose Tissue at 7 Years of Age
Date not available
Effects of Zinc, Magnesium and Vitamin B6 (ZMA) Supplementation on Serum IGF-I, IGFBP-3 and Testosterone Concentrations in Young Athletes
Date not available
Low insulin-like growth factor-II (IGF-II) concentration predicts weight gain in normal weight subjects with type 2 diabetes
2005-01-0303Jan2005
Hypoxia-ischaemia and the insulin-like growth factor (IGF) family at birth
2003-01-0303Jan2003
Serum IGF-I, IGFBP-3 and Als Concentrations and Physical Performance in Young Swimers During a Training Season
Date not available
Further analyses on the role of IGF-I in the diagnosis of GH deficiency (GHD) in children
Date not available
Monitoring insulin-like growth factor-I and IGF binding protein-3 in children and adolescents on GH treatment using filter paper blood spots
2002-01-0303Jan2002
Evaluation of acromegaly status following surgery by OGTT, GH day curve and IGF-I: relationships between these parameters
2007-01-0303Jan2007
IGF-I response to pasireotide LAR treatment in acromegaly is mainly driven by somatostatin receptor subtype 2 expression
2018-08-0505Aug2018
Dehydroepiandrosterone (DHEA) replacement enhances IGF-I generation in hypopituitary patients on growth hormone replacement
2005-01-0303Jan2005
Testosterone enhances the effect of growth hormone (GH) to increase IGF-I but exerts an anabolic effect that is independent of GH action
2003-01-0303Jan2003
Sequential Measurements of IGFI Serum Concentrations in Patients With Severe Primary IGFI Deficiency (SPIGFD) and Growth Failure Treated With Recombinant IGFI (Increlex<sup>&#174;</sup>)
Date not available
Study on IGF(CA)19 gene polymorphism in adults with GH deficiency
2012-01-0505Jan2012
Targeting the IGF-IR system in pituitary tumors <i>in vitro</i>: antiproliferative action &#38; pitfalls
2012-01-0505Jan2012
Exogenous growth hormone administration effects organ weights but does not markedly change serum IGF-I levels in common mice
2009-01-0404Jan2009
Pubertal Onset in 1572 Girls with Short, Normal and Tall Stature: Associations to Height, Serum IGF-I and PAPP-A2 Genotypes
Date not available
A comparison of the <em>in vitro</em> production of IGFs, IGFBP-4 and PAPP-A in cultures of visceral and subcutaneous adipose tissue fragments from obese subjects
2013-01-0404Jan2013
4.5. Growth and adult height in girls with Turner syndrome following IGF-I titrated growth hormone treatment
Date not available
Are pappalysins and stanniocalcins involved in modifying the bioavailability of IGF-I in children with onset of type 1 diabetes mellitus?
Date not available
Discrepant GH and IGF-I values in the evaluation of treated acromegalic patients; an ongoing challenge. A meta-analysis
Date not available
The involvement of GH-IGF-I axis in a mouse model of type II diabetic nephropathy
2006-04-1212Apr2006
The effect of insulin-like growth factor I (IGF-I) on initiation of follicle growth in normal and polycystic ovaries <i>in vitro</i>
2004-01-0303Jan2004
A comprehensive overview of the changes in IGF system peptides in the follicular fluid (FF) of women with Polycystic Ovarian Syndrome (PCOS) and their relationships with BMI and HMGB1
Date not available
Generation of normative data on serum insulin-like growth factor I (IGF-I) in healthy school children of a north indian city
Date not available
Metabolic impact of IGF(CA)19 gene polymorphism on the response to GH therapy in adult GH-deficient (GHD) patients
2013-01-0404Jan2013
The complex Relationship between the GH/IGF Axis and Aging and Longevity &#150; the Interface with Diet and Mitochondrial Peptides
Date not available
Effects of human insulin and insulin aspart preparations on levels of IGFI, IGFBPs and IGFI bioactivity in patients with type 1 diabetes
2013-01-0404Jan2013
Targeting either GH or IGF-I levels during somatostatin analogue treatment in patients with acromegaly: A randomized, investigator-initiated multicenter study
2017-03-0505Mar2017
Regulation of implantation by interaction between the IGF receptor (IGF1R) and miR-145
2014-01-0303Jan2014
Relationship of Birth Gestational Age with the Ratio between IGF2 and IGF Binding Protein 3 in Blood Serum Beyond Influences of Gender, Small-For-Gestational-Age Status, Caesarean Section, Caloric Intake, and Predominant Breast Milk Feeding in the Not-Life-Threatened Newborn: Relevance of Parenteral Nutrition
Date not available
Association of malaria in pregnancy with maternal metabolic biomarkers, cord blood IGF-I and birth size in Nigerian infants: &#145;The Ibadan Growth and Vascular Health Study&#146;
2010-01-1111Jan2010
Pre-treatment IGF-I concentrations predict radiographic osteoarthritis in acromegalic patients with long-term cured disease
2009-01-0404Jan2009
Altered IGF-I signalling in children born small for gestational age without catch up growth
2009-01-0303Jan2009
Beneficial synergistic interactions of TNF-&#945; and IL-6 in C2 skeletal myoblasts; potential cross-talk with IGF system
2008-01-0404Jan2008
Serum concentration of insulin-like growth factor I (IGF-I): reference values for adult Romanian population: Preliminary results
2018-08-0505Aug2018
4.10. IGF-I in cord blood is predictive of final height in monozygotic twins with intratwin birth weight differences
Date not available
Increased intraovarian levels of noradrenaline and NGF precede the follicular changes in the rat ovary at the end of reproductive period
Date not available
Characteristics, Effectiveness and Safety Data for Patients with Growth Failure Treated with Recombinant IGF-I (rhIGF-I) and Achieving Adult or Near-adult Height (AH): Results from the European Increlex<sup>&#174;</sup> Growth Forum Database (EU-IGFD) Registry
Date not available
Effects of combined treatment with cabergoline and somatostatin analogues (SAA) on GH and IGF-I levels and tumor volume in patients with acromegaly not fully responsive to SAA
Date not available
IMPACT OF MATERNAL NUTRIENT RESTRICTION IN EARLY TO MID GESTATION ON INSULIN-LIKE GROWTH FACTOR-I (IGF-I) RECEPTOR mRNA ABUNDANCE IN THE OVINE PLACENTA
2001-01-1111Jan2001
TGF-&#946; signaling and the microRNA machinery
2013-01-0404Jan2013
PAPP-A2 Gene Mutation Effects on Glucose Metabolism and Bone Mineral Density and Response to Therapy with Recombinant Human IGF-I
Date not available
Optimising diagnostic performance of IGF-I and IGFBP-3 measurement: importance of reference range and cut-off value
Date not available
Urinary bisphenol A (BPA) and its relation to insulin growth factor (IGF) system in polycystic ovary syndrome
Date not available
Evaluation of hypotalamic-pituitary-gonadal (HPG) axis and GH-IGF-I axis in adult patients with celiac disease
Date not available
Pituitary macroadenoma: is IGF-I measurement enough to exclude growth hormone excess? 3 case reports
2005-01-0303Jan2005
Normalisation of serum IGF-I by pegvisomant is not associated with a reduction in median nerve size in patients with active acromegaly
2003-01-1111Jan2003
Bone Status in a Patient with IGF-I Receptor Deletion Syndrome: Bone Quality and Structure Evaluation Using DXA, pQCT, and QUS
Date not available
FGF 23 measurements in children with fibrous dysplasia: useful or not?
Date not available
Lessons From a Patient Carrying Both an 11p Paternal Duplication and 15q Deletion, Illustrating the Roles of IGF2 and IGF1R in Growth Regulation
Date not available