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Adrenal Aldosteronism

Aldosteronism Addison’s disease Mineralocorticoids Cortisol Sodium Hypertension

New test uses urine samples and AI to detect hypertension

Scientists develop a new non-invasive method to identify primary aldosteronism

Sex differences in the link between obesity and primary aldosteronism

Emergency strategies may improve survival of children with autosomal recessive pseudohypoaldosteronism type 1

New treatment pathway for hyperaldosteronism identified

Left adrenal vein aldosterone ratio may help predict right-sided unilateral disease in primary aldosteronism

ACTH on aldosterone secretion in aldosteronism

PCP4: a regulator of aldosterone synthesis

ECE 2013 Day 4 - Programme Highlights

Renal outcome in hyperaldosteronism

Aldosteronism linked to poor bone health (NewsMedical, 7 June 2012)

Spontaneous remission of idiopathic aldosteronism

Can both anxiety and high blood pressure be explained by a hormonal disturbance? (AlphaGalileo, 3 October 2011)

High blood pressure may be caused by mutation in adrenal gland (EurekAlert, 10 Feb 2011)

Resource not read: Query Programmes

Primary hyperaldosteronism

corticosteroids

Addison's disease

Adrenocorticotropic hormone

Melanocyte-stimulating hormone

Congenital adrenal hyperplasia

Patient factsheet: UK guidance on differences/disorders of sex development in children

Multiple endocrine neoplasia type 2B

Multiple endocrine neoplasia type 2A

Glucocorticoid excess in primary aldosteronism

Keeping up with the genes in primary aldosteronism

Adrenal and Cardiovascular Network: an update

A word from the Editor

AN INTERVIEW WITH… PAUL STEWART

The rhythms of life: the importance of glucocorticoid pulsatility

Serum 18 hydroxycortisol identifies aldosteronoma in the differential diagnosis of primary aldosteronism

Daily profiles of aldosterone secretion in primary aldosteronism

Primary aldosteronism

Short-term blood pressure response to mineralocorticoid-receptor blockade in aldosteronisms: primary hyperaldosteronism vs aldosterone-associated hypertension/low-renin hypertension

The Urinary Aldosterone in the Diagnosis of Primary Aldosteronism

The primary aldosteronism rollercoaster: hypoaldosteronism as a potential postoperative complication

Severe hypoaldosteronism after unilateral adrenalectomy for aldosteronoma: Case report

Treating Primary Aldosteronism with New Aldosterone Receptor Antagonists

Prolonged hypoaldosteronism after unilateral adrenalectomy for primary aldosteronism: a report of two cases

GnRH in primary aldosteronism

8.13. Diagnosis and treatment of primary aldosteronism

8.17. Pathogenesis and treatment of primary aldosteronism

The evolution of primary aldosteronism

Genetics of primary aldosteronism

Sporadic solitary aldosterone- and cortisol-cosecreting adenomas: a subtype of primary aldosteronism

Molecular mechanisms in primary aldosteronism

Genomic profile in primary aldosteronism

Aldosterone/direct renin ratio (ADRR) in the screening of patients with primary aldosteronism

Potassium channels in primary aldosteronism

Aldosterone variability in patients with primary aldosteronism undergoing adrenal vein sampling

Primary Aldosteronism: Is low K+ always the key?

Primary aldosteronism and pregnancy

Primary Aldosteronism due to Adrenal Adenoma

Expression of CYP11B2 and CYP11B1 immunostaining in primary aldosteronism

Long-term consequences of primary aldosteronism

LC-MS/MS measurement for urinary aldosterone improves primary aldosteronism screening

Glucocorticoid axis in patients with primary aldosteronism

Aldosterone concentration in the adrenal vein predicting the subtype of primary aldosteronism

DIAGNOSIS OF HYPOALDOSTERONISM

Immunohistochemical characteristics of adrenal tumors in patients with primary aldosteronism

Regulation of aldosterone synthase expression in normal adrenal and primary aldosteronism

Integrating genetics and genomics in primary aldosteronism

Primary aldosteronism : Study of 09 cases

Ascending aorta dilatation in primary aldosteronism: a new deleterious consequence of aldosterone excess

First phase insulin secretion is impaired by aldosterone excess in primary aldosteronism

Severe hypoaldosteronism after unilateral adrenalectomy for primary hyperaldosteronism

Primary Aldosteronism and Cortisol Cosecretion in a Patient with Adrenal Adenoma

Assessment of serum adropin concentrations in primary aldosteronism

Occult aldosteronoma mimicking degenerative spine disease

Prevalence of neoplasms in patients with primary aldosteronism

8.10. Treatment of Primary Aldosteronism with mTORC1 Inhibitors

Audit of adrenal vein sampling for primary aldosteronism

The frequency of confirmed primary hyperaldosteronism in patients with high aldosteron renin ratio

Non-surgical therapy of primary aldosteronism

The role of early postoperative aldosterone in saline infusion test in the prediction of primary aldosteronism remission

Heparin-induced hypo-aldosteronism and hyperkalemia

Heparin-induced hypo-aldosteronism and hyperkalemia

Primary aldosteronism during 20072011 in Iceland

Predictors of bilateral and unilateral primary aldosteronism: a retrospective observational study

Screening for aberrant peptide hormone responsiveness in primary aldosteronism

Screening of primary aldosteronism among egyptian hypertensive population

Endocrine hypertension due to primary aldosteronism

Recalculating renin and aldosterone to improve specificity in the diagnosis of primary aldosteronism

Analysis of circulating microRNAs in primary aldosteronism

Simultaneous assays of aldosterone and renin concentrations in just ten minutes could change the clinical assessment for the diagnosis of primary aldosteronism

Screening for primary aldosteronism in a secondary care diabetes population

Hair cortisol in patients with primary aldosteronism

Hypokalaemic cardiac arrest  a rare presentation of primary aldosteronism

Evaluation of aldosterone to renin concentration ratio as a reliable screening parameter for primary aldosteronism applying currently available assays

Glucocorticoid production in primary aldosteronism  from mechanisms to clinical implications

Primary aldosteronism: follow up of 17 cases

Factored aldosterone can help distinguish mineralocorticoid resistance from aldosterone deficit hypoaldosteronism

<p>Acquired hypoaldosteronism as classified by circulating aldosterone levels: characteristics</p>

Prevalence of primary aldosteronism in Chinese patients with resistant hypertension

Congenital hyperreninemic hypoaldosteronism due to aldosterone synthase deficiency

New diagnostic methods for primary aldosteronism with specific antibodies

Adrenal venous sampling vs imaging for primary aldosteronism

Pathophysiological significance of CYP11B2 immunohistochemical staining in primary aldosteronism

Glucocorticoid remediable aldosteronism. A Northern Ireland experience

Are we missing patients with primary aldosteronism (PA) if we require both elevated aldosterone: renin ratio (ARR) and elevated aldosterone levels?

Bilateral primary aldosteronism prediction by Integer scoring system

Bilateral primary aldosteronism prediction by Integer scoring system

A challenging case of primary aldosteronism presenting in pregnancy

A challenging case of primary aldosteronism presenting in pregnancy

Retrospective analysis of diagnostic and treatment outcomes of primary aldosteronism

Primary aldosteronism: insights from a single center cohort

Prolactinoma and primary aldosteronism: is there a causal link?

Primary Aldosteronism in Iceland, nationwide results from 20122016

The effect of adrenalectomy on metabolic parameters in patients with primary aldosteronism

Histopathology and post-surgical outcomes of surgically treated patients for primary aldosteronism

Normotensive hypokalemic primary aldosteronism: How is this Possible?

Intermittent primary aldosteronism  another hurdle in the Conns story?

Captopril challenge test  is it useful for the diagnosis of primary aldosteronism?

Comparison between aldosterone and renin measurement by chemiluminescent immunoassay and RIA for the diagnosis of primary aldosteronism

The genetic etiology of ACTH-dependent aldosterone hypersecretion in hypertensive patients without Primary Aldosteronism

Severe hyperkalemia and unmasking of renal disease following adrenalectomy for aldosteronoma

The saline infusion test with mass spectrometric measurements of aldosterone in patients tested for primary aldosteronism

The renin-angiotensin-aldosteron system in primary adrenal insufficiency

Characteristics of patients with normal adrenal imaging in primary aldosteronism

Predictors for cure and normotension after adrenalectomy for primary aldosteronism

Revised guidelines for finding and treating primary aldosteronism

The infradiagnosis of primary aldosteronism as a public health problem

Primary aldosteronism: clinical presentation and management about 2 cases

Adrenal vein sampling vs imaging in primary aldosteronism

Adrenal vein sampling vs imaging in primary aldosteronism

Urine steroid metabolomics as a diagnostic tool in primary aldosteronism

Infant with primary hypoaldosteronism due to aldosterone synthase deficiency

Primary aldosteronism and microprolactinoma: a new syndromic variant?

Time to change the focus with a new treatment for primary aldosteronism

Primary aldosteronism associated with subclinical Cushing syndrome

Remission rate of primary aldosteronism after unilateral adrenalectomy

Remission rate of primary aldosteronism after unilateral adrenalectomy

Prognostic value of contralateral suppression on eGFR after surgery in primary aldosteronism

Postural orthostatic tachycardia syndrome unmasked by successful treatment of primary aldosteronism

Normotensive primary aldosteronism in a young woman taking minipill – case report

Aldosterone:metanephrine ratio better predicts laterality in patients with primary aldosteronism and mild autonomous cortisol co-secretion than aldosterone:cortisol ratio

Subtyping of primary aldosteronism in patients with partially successful adrenal vein sampling

Diagnostic accuracy of the aldosterone to active renin ratio in detecting primary aldosteronism: the graz endocrine causes of hypertension (GECOH) study

Evaluation of angiotensin II in primary aldosteronism and other forms of hypertension  a preliminary study

6.11. Identification of risk loci for primary aldosteronism in genome-wide association studies

ACTH stimulation test for study of primary aldosteronism

Early post-operative ACTH-stimulated aldosterone predicts long-term biochemical outcome in primary aldosteronism

Predictive performance of aldosterone-to-renin ratio in the diagnosis of primary aldosteronism in patients with resistant hypertension

Combined primary aldosteronism and preclinical Cushing's syndrome due to a large adrenocortical adenoma

Aldosterone/Renin Ratio as Key Player in the Diagnosis of Primary Hypoaldosteronism in Newborns and Infants

18-Oxocortisol measurement in adrenal vein sampling as a biomarker for subclassifying primary aldosteronism

Dissociation of subtype diagnosis by various criteria on adrenal venous samplings in primary aldosteronism

Becoming of patients with primary aldosteronism according to their treatment

Under-expression of the TWIK-related acid-sensitive K<sup>+</sup> channel 2 (TASK-2) gene is a hallmark of aldosterone producing adenoma causing human primary aldosteronism

Cardiovascular and cerebrovascular burden associated with primary aldosteronism: a monocentric study

Metabolic and hormonal profile in primary aldosteronism as compared with essential hypertension

Aortic root dilatation in primary aldosteronism: is treatment effective in reducing aortic damage?

Hyporeninemic hypoaldosteronism with severe hyperkalemia following adrenalectomy for primary hyperaldosteronism : a case report

Primary aldosteronism  management can be challenging and complex

8.2 A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

Distinguishing different subtypes of aldosterone-producing adenoma by histological, immunohistochemical and radiological features; a basis for individualised treatment strategies in primary aldosteronism?

Investigating children of glucocorticoid remediable aldosteronism patients'  early testing is beneficial

Gene polymorphisms related to metabolic and cardiac complications in patients with primary aldosteronism

Primary aldosteronism: Small molecule antagonists of mutant KCNJ5 potassium channels

Prevalence and significance of hypokalemia in primary aldosteronism: a retrospective study

Prevalence of primary aldosteronism among hypertensive patients (preliminary results)

Imaging of adrenal aldosterone synthase expression in patients with primary aldosteronism  a first-in-human study with [<sup>18</sup>F]aldoview PET-CT

Confirmatory testing of primary aldosteronism with saline infusion test and LC-MS/MS

Modulation of calcium signaling on demand to decipher the molecular mechanisms of primary aldosteronism

18-Hydroxycorticosterone, 18-hydroxycortisol and 18-oxocortisol in the diagnosis of primary aldosteronism and its subtypes.

Posterior reversible encephalopathy syndrome (PRES) in a patient with primary aldosteronism

New germline mutation in CACNA1H calcium channel causing primary aldosteronism

Selective adrenal venous sampling is not always useful in primary aldosteronism

Use of the 250 mcg short synacthen test in the diagnosis of primary aldosteronism

Is adrenal computed tomography accurate for the diagnosis of unilateral primary aldosteronism? A retrospective international cohort study

ARR screening using IDS-iSYS aldosterone and direct renin: effects of medication in essential and renovascular hypertension, Cushing's syndrome and primary aldosteronism

A case of primary aldosteronism and Hashimotos thyroiditis  complicated relationship or pure coincidence?

Circulating levels of miR24-1 cluster microRNAs are increased in primary aldosteronism

Primary aldosteronism  results from the first Portuguese multicentre study

Posture-responsive primary aldosteronism  the utility of seated saline suppression test

Evaluation of renal function of primary aldosteronism between pre- and post-treatment

Intact endothelial epoxyeicosatrienoic acids pathway in primary aldosteronism – the route to new treatment strategies?

Prolonged zona glomerulosa insufficiency causing hyperkalemia in primary aldosteronism following adrenalectomy

Aldosterone measurement in the Diagnosis of primary aldosteronism  comparison between two automated immunoassays and two liquid chromatography tandem mass-spectrometry methods

Adiponectin gene polymorphisms in primary aldosteronism and their relation to the metabolic syndrome

Prevalence and Characteristics of Familial Hyperaldosteronism: the PATOGEN study (Primary Aldosteronism in TOrino - GENetic forms).

Auditing Adrenal Vein Sampling for Primary Aldosteronism to highlight existing challenges

Evaluating the diagnostic capacity of the saline infusion and captopril challengetests for primary aldosteronism

The value of high effective liquid chromatography in the diagnosis of primary aldosteronism

Comparison of strategies for biochemical diagnosis of primary aldosteronism in German academic centres

The sodium to urinary sodium to potassium to urinary potassium (SUSPUP) ratio in primary aldosteronism

How do I confirm biochemical diagnosis of primary aldosteronism?

Hyperreninemic Hypoaldosteronism: Clinical and Genetic Features in Pediatric Patients

Metabolic parameters in patients with primary aldosteronism: relation to snps of the adiponectin gene

Hyporeninaemic hypoaldosteronism in surgically cured Conns syndrome

Renin assay interference may conceal the diagnosis of primary aldosteronism

Renin assay interference may conceal the diagnosis of primary aldosteronism

Primary aldosteronism: more common than once thought: Two clinical cases

Prevalence of primary aldosteronism among hypertensive population in Trabzon City, Turkey

Adrenal venous sampling should be performed before adrenalectomy in primary aldosteronism?

Prevalance of primary aldosteronism in hypertensive patients: epidemiological data from a tertiary centre

Salivary aldosterone is a useful marker of serum aldosterone in normotensive individuals

Confirmatory tests for diagnosis of primary aldosteronism among Chinese hypertensives

Prevalence of primary aldosteronism in patients with acute stroke: A prospective study

Case of prolonged hypoaldosteronism after unilateral adrenalectomy for Conns syndrome

Prevalence of primary aldosteronism and association with cardiovascular complications in patients with resistant and refractory hypertension

Predicting factors of the post-surgical decline in renal function in patients with primary aldosteronism

Metabolic syndrome among patients with primary aldosteronism: a common feature?

Primary results from MATCH: A randomised controlled trial in primary aldosteronism

Low ACTH and cortisol production following adrenalectomy for primary aldosteronism

Measurement of metanephrine in adrenal venous sampling may help subtyping primary aldosteronism

Primary hypoaldosteronism due to aldosterone synthase deficiency in a small for gestational age born infant

Magnetic iron oxide nanoparticles for the delivery of thermal therapy for the treatment of primary aldosteronism

Renal function in patients with primary aldosteronism: comparison with essential hypertension

Against  Adrenal venous sampling vs. imaging for primary aldosteronism: beware of the caveats!

New perioperative imaging techniques, immunohistochemistry and genetic analysis to investigate the suitability of laparoscopic partial adrenalectomy in primary aldosteronism

Clinical features and complication profile of arterial hypertension in patients with primary aldosteronism

Optimal application of captopril challenge test in the diagnosis of primary aldosteronism

A patient with two forms of PA  pituitary adenoma and primary aldosteronism

Paradoxical worsening of lipid metabolism after successful treatment of primary aldosteronism

Long-term outcome from unilateral adrenalectomy in patients with primary aldosteronism

Unlocking the metabolic mysteries: exploring metabolic syndrome in primary aldosteronism

11C-Metomidate PET/CT Identifies Unilateral Primary Aldosteronism in a Multi-ethnic Cohort

Obstructive sleep apnea in primary aldosteronism is associated with cortisol cosecretion

Biochemical and clinical cure of primary aldosteronism by ultrasound-guided endoscopic radiofrequency ablation

Prediction of endogenous mineralocorticoid receptor activity by depressor effects of mineralocorticoid receptor antagonists in patients with primary aldosteronism

Repeated hormonal and radiological evaluation of hypertensive patients is necessary for correct primary aldosteronism diagnosis and treatment

Renin: a possible novel marker for the efficacy of pharmacological treatment of primary aldosteronism

In primary aldosteronism, plasma aldosterone concentration is an independent risk factor for albuminuria, and the higher baseline urinary albumin excretion predicts the less glomerular filtration rate after treatment

Reduction of albuminuria after surgical and medical treatment of primary aldosteronism

Clinical presentation and management of primary aldosteronism in late childhood and adolescence: Experience in an outpatient hypertension clinic

Hyponatraemia and falls in the elderly due to hypoaldosteronism

Adrenal reserve and glucocorticoid requirements post unilateral adrenalectomy for primary aldosteronism

Discordance between imaging and adrenal vein sampling in primary aldosteronism

Treatment strategy and outcome with primary aldosteronism: a nationwide longitudinal cohort based study

Primary hyperaldosteronism