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Adrenal Bone Cardiovascular Diabetes Endocrine-Disrupting Chemicals Endocrine-Related Cancer Metabolism Neuroendocrinology Obesity Reproduction Steroid and Steroidogenesis Thyroid

Steroid and Steroidogenesis Aldosterone

Estrogen Corticosteroids Mineralocorticoid Aldosterone Androgens Testosterone Gonadotropin Cholesterol Gonads Steroid Glucocorticoids

Scientists develop a new non-invasive method to identify primary aldosteronism

Aldosterone excess linked to chronic kidney disease

Non-invasive method developed to detect adrenal adenomas

Young obese women at early risk for cardiovascular disease

Young obese women at early risk for cardiovascular disease

Avoiding severe complications of postoperative adrenal insufficiency

Avoiding severe complications of postoperative adrenal insufficiency

Higher aldosterone levels may make women more sensitive to high salt diet

High aldosterone levels are related to diabetes

Aldosterone increases response of cell brains that cause salt cravings

Hypertensive women may benefit from drugs that block aldosterone

Aldosterone hormone linked to alcohol use

Left adrenal vein aldosterone ratio may help predict right-sided unilateral disease in primary aldosteronism

Journal-based learning update

ACTH on aldosterone secretion in aldosteronism

An Endocrinologist’s guide to Poland

PCP4: a regulator of aldosterone synthesis

Announcing the death of Professor James Francis Tait, FRS

ACE inhibition in hypercapnia

Tiny adrenal tumours 'cause high blood pressure' (BBC News Online, 5 August 2013)

Regulatory effects of aldosterone on apelin expression

ECE 2013 - deadline for abstract submissions - 13 January 2013

ECE 2013 - abstract submission now open!

Winners of 2013 Geoffrey Harris and European Journal of Endocrinology prizes announced

New articles on aldosterone and Anti-Mullerian hormone

Adrenal crises in 21-OHD patients

Common genetic mutation increases sodium retention, blood pressure (EurekAlert, 30 May 2012)

Spontaneous remission of idiopathic aldosteronism

PPAR-gamma and aldosterone production

Undergraduate Essay Prize Winners

Aldosterone - the key to curing high blood pressure? (AlphaGalileo, 9 April 2008)

Imaging of Adrenal Aldosterone Synthase Expression in Patients with Primary Aldosteronism – A First-in-Human study with [18F]AldoView PET-CT

Development of [18F]AldoView as the first highly selective aldosterone synthase PET tracer for imaging of patients with primary hyperaldosteronism

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosteroneproducing adenomas presenting in puberty, pregnancy or menopause

SLC35F1, a potential marker for aldosterone producing cell clusters

The role of “stress” in aldosterone-mediated hypertension: circumstantial evidence from the “stress ...

APEX1, a novel, negative regulator of aldosterone synthase activity, differentially binds to a singl...

Altered miR-125 and miR-134 expression in aldosterone-producing adenoma and post-transcriptional reg...

Aldosterone action and the mineralocorticoid receptor

Aldosterone Induced Vascular Inflammatory Disease: Mechanisms and Implications for Clinical Practice

An aldosterone crisis

A KCNJ5-mutant aldosterone producing adenoma (APA) with failure to suppress on dexamethasone and fal...

OC8 - Dexamethasone-suppressed PET CT, using an 18F-ligand (‘CETO’), allows non-invasive diagnosis of unilateral aldosterone-producing adenoma, and prediction of complete clinical cure after adrenalectomy

The PremAldo Study: Impaired Aldosterone Signaling Worsens Renal Sodium Loss in Preterm Infants

Aldosterone and mineralocorticoid receptor as inducers of immune markers in peripheral blood mononuc...

Epigenetic regulation of aldosterone synthase gene, CYP11B2 by potassium

Activation of the Renin-Angiotensin II-Aldosterone-System Leads to Increases in Extracellular Protei...

Activators of AMP-activated protein kinase regulate adipocyte aldosterone secretion and mineralocort...

MicroRNA profiling of H295R cells following stimulation of aldosterone production: a bioinformatic s...

Protein kinase D as a modulator of aldosterone action in the kidney

Resource not read: Query You and Your Hormones

IMMUNOASSAY MAY NOT REVEAL LOW ALDOSTERONE IN COVID-19

NO EXTRA-ADRENAL ALDOSTERONE PRODUCTION IN VARIOUS HUMAN CELL LINES

Keeping up with the genes in primary aldosteronism

Hilary M Drane (née Grundy)

Hyponatraemia in nivolumab-induced adrenal failure

Hypertension in pregnancy due to DOC-secreting tumour

CORTICOSTEROIDS: LITTLE CHANGE?

Mineralocorticoid receptor signalling in the naked mole-rat

Your new General Secretary and Programme Secretary

Roger Ekins obituary

AN INTERVIEW WITH… PAUL STEWART

AN INTERVIEW WITH…MORAG YOUNG, JOURNAL DEPUTY EDITOR

New developments: CRG and the endocriology dashboard

The endocrine system: a friend in dark places?

EARLY CAREER CLINICIAN: MILD AUTONOMOUS CORTISOL SECRETION: AN UNDERESTIMATED CARDIOMETABOLIC DISEASE ICEBERG

The Endocrinologist 132.pdf

Endocrinologist 129 Web

Endocrinologist 146 Web

Endocrinologist 152 Final For Web

ScreenSummerEndoComplete.pdf

Endocrinologist 145 Web

Endocrinologist 130 Web

Endocrinologist 142 Web (1)

Endocrinologist 142 Web

Endocrinologist 150 Web

Endocrinologist 151 Final

Endocrinologist 121 Web final.pdf

Endocrinologist 122 FINAL Web.pdf

The Endocrinologist 114 Web.pdf

Endocrinologist 124 Web

Endocrinologist 128 Web Updated

Endocrinologist 136 Web

Endocrinologist 140 Web

Endocrinologist 143 Web

The Endocrinologist 115 Web FINAL.pdf

The Endocrinologist Autumn 14 -website.pdf

The renin-angiotensin-aldosteron system in primary adrenal insufficiency

Daily profiles of aldosterone secretion in primary aldosteronism

The frequency of confirmed primary hyperaldosteronism in patients with high aldosteron renin ratio

The Urinary Aldosterone in the Diagnosis of Primary Aldosteronism

Fluasterone buccal tablets: a promising therapy for the metabolic effects of hypercortisolemia and cushing syndrome

Salivary aldosterone is a useful marker of serum aldosterone in normotensive individuals

Treating Primary Aldosteronism with New Aldosterone Receptor Antagonists

Extra-adrenal aldosterone biosynthesis

An aldosterone crisis

Serum 18 hydroxycortisol identifies aldosteronoma in the differential diagnosis of primary aldosteronism

Aldosterone variability in patients with primary aldosteronism undergoing adrenal vein sampling

Interference in aldosterone assay revealed by hemolysis.

Aldosterone/direct renin ratio (ADRR) in the screening of patients with primary aldosteronism

Aldosterone and parathyroid hormone  is there a connection?

Sporadic solitary aldosterone- and cortisol-cosecreting adenomas: a subtype of primary aldosteronism

LC-MS/MS measurement for urinary aldosterone improves primary aldosteronism screening

Congenital hyperreninemic hypoaldosteronism due to aldosterone synthase deficiency

Aldosterone action and the mineralocorticoid receptor

Aldosterone, mineralocorticoid receptors and cardiovascular risk: what's new?

Aldosterone concentration in the adrenal vein predicting the subtype of primary aldosteronism

Aldosterone and cardiovascular function: a lifetime of damage

Are we missing patients with primary aldosteronism (PA) if we require both elevated aldosterone: renin ratio (ARR) and elevated aldosterone levels?

Regulation of aldosterone synthase expression in normal adrenal and primary aldosteronism

Towards an aldosterone producing cell line from an aldosterone producing adenoma

Recalculating renin and aldosterone to improve specificity in the diagnosis of primary aldosteronism

PCOS phenotypes and their relationship to aldosterone levels

Ascending aorta dilatation in primary aldosteronism: a new deleterious consequence of aldosterone excess

First phase insulin secretion is impaired by aldosterone excess in primary aldosteronism

Inhibition of C<sub>17,20</sub>-lyase activity by new 17β-exo-heterocyclic androsterone derivatives

Serum and plasma aldosterone levels and the respective aldosterone/plasma renin indices in healthy blood donors

Implication of serotonin in the physiopathology of aldosterone-producing adenoma

The role of early postoperative aldosterone in saline infusion test in the prediction of primary aldosteronism remission

Aldosterone:metanephrine ratio better predicts laterality in patients with primary aldosteronism and mild autonomous cortisol co-secretion than aldosterone:cortisol ratio

Reference range data on androsterone glucuronide in healthy male and female volunteers and clinical uses of the assay

Conn's syndrome with normal plasma renin aldosterone ratio

Impact of antihypertensive drugs, sodium intake and potassium plasma concentrations on plasma aldosterone and plasma renin aktivity

Protein kinase D as a modulator of aldosterone action in the kidney

CYP11B2 polymorphism affects the aldosterone  renin ratio?

Simultaneous assays of aldosterone and renin concentrations in just ten minutes could change the clinical assessment for the diagnosis of primary aldosteronism

Androsterone Glucuronide to dehydroepiandrosterone sulphate ratio is higher in obese Caucasian women with Polycystic Ovary Syndrome

Comparison of a RIA assay and a CLIA assay for aldosterone determination

Comparison between aldosterone and renin measurement by chemiluminescent immunoassay and RIA for the diagnosis of primary aldosteronism

The genetic etiology of ACTH-dependent aldosterone hypersecretion in hypertensive patients without Primary Aldosteronism

Visinin-Like Protein-1 in the regulation of aldosterone biosynthesis

Clinical and Biochemical Phenotype of Aldosterone Synthase Deficiency

Influence of drospirenone on reninangiotensinaldosterone system evaluation

Evaluation of diagnostic cut-offs for aldosterone-renin ratio using iSYS assays for aldosterone and direct renin

Heritability of plasma aldosterone levels and genetic variation association with the aldosterone synthase (<i>CYP11B2</i>) and 11beta-hydroxylase (<i>CYP11B1</i>) genes

Aldosterone deficiency type 1 due to mutation of the CYP11B2

Aldosterone synthase deficiency due to a novel mutation in <em>CYP11B2</em>

The saline infusion test with mass spectrometric measurements of aldosterone in patients tested for primary aldosteronism

Factored aldosterone can help distinguish mineralocorticoid resistance from aldosterone deficit hypoaldosteronism

SLC35F1, a potential marker for aldosterone producing cell clusters

Genes mediating cell growth in aldosterone-producing adenomas

Development of a non-isotopic immunoassay for the measurement of aldosterone in saliva

Superselective adrenal venous sampling for intra-adrenal localization of aldosterone hypersecretion.

Prediction of fatal stroke by high serum aldosterone levels

Evaluation of aldosterone to renin concentration ratio as a reliable screening parameter for primary aldosteronism applying currently available assays

The role of stress related aldosterone secretion in essential hypertension

Regulation of aldosterone secretion: from physiology to disease

KCNJ5 mutations in Japanese patients with aldosterone-producing adenomas

The measurement of the reninangiotensinaldosterone system in patients with adrenal tumors with arterial hypertension

Short-term blood pressure response to mineralocorticoid-receptor blockade in aldosteronisms: primary hyperaldosteronism vs aldosterone-associated hypertension/low-renin hypertension

Clinical case of aldosterone-producing adrenocortical carcinoma

Bioinformatic analysis of microRNAs associated with aldosterone secretion

Development of a mouse hypertension model induced by aldosterone excess

<i>In vitro</i> expression of catalytically active human aldosterone synthase

CYP11B2 DNA methylation pattern is discordant in aldosterone-producing adenomas and in concurrent aldosterone-producing cell clusters

Polydipsia, Hyponatremia and a Biochemical Profile of Aldosterone Synthase Deficiency

Infant with primary hypoaldosteronism due to aldosterone synthase deficiency

Occult aldosteronoma mimicking degenerative spine disease

<em>PRKACA</em> somatic mutations are rare in aldosterone-producing adenomas.

Molecular and immunohistochemical analysis of aldosterone producing adenomas

Use of diurnal rhythm in salivary aldosterone to discriminate between bilateral adrenal hyperplasia and aldosterone producing adenoma

Variation in the aldosterone synthase gene may alter gene transcription via altered transcription factor binding

The response of infants adrenal gland and salt appetite, aldosterone and Na serum level to mothers salt consumption

Expression of prolactin receptor in aldosterone-producing adrenal adenomas

A rare case of Aldosterone synthase deficiency presenting with Hypertension.

Discovery of putative aldosterone-regulating microRNAs by analysis of <em>in vitro</em> and <em>in vivo</em> microRNA profiles

Primary aldosteronism

Aldosterone measurement: performances of a new fully automated chemilunescence-based immunoassay

Abiraterone related hyponatremia

An investigation into the role of parathyroid hormone in the regulation of aldosterone secretion in hypertensive cardiovascular patients

Acute aldosterone responses to ACTH predict both cortisol responses and blood pressure

Early post-operative aldosterone concentration can be used to assess outcome from adrenalectomy in aldosterone producing adenoma

Early post-operative ACTH-stimulated aldosterone predicts long-term biochemical outcome in primary aldosteronism

Predictive performance of aldosterone-to-renin ratio in the diagnosis of primary aldosteronism in patients with resistant hypertension

18-oxocortisol synthesis in aldosterone-producing adrenocortical adenoma and significance of KCNJ5 mutation status

Diagnostic accuracy of the aldosterone to active renin ratio in detecting primary aldosteronism: the graz endocrine causes of hypertension (GECOH) study

Epigenetic regulation of aldosterone synthase gene, CYP11B2 by potassium

Severe hyperkalaemia and hyponatramia with grossly elevated aldosterone: pseudohypoaldosteronism

Characteristics of aldosterone-producing adenomas: a tissue microarray study

Renin-angiotensin-aldosterone system in patients with primary hyperparathyroidism

Investigating Changes in Plasma Aldosterone Concentrations Following ACTH Stimulation in Healthy Individuals: A Systematic Review and Meta-Analysis on the Influence of ACTH on Aldosterone Secretion

Low SLC26A2 expression in adrenal cells is associated with high aldosterone output

Establishment of a mutagenesis screen to identify mice with high aldosterone levels

The effect of PCSK9 Inhibitor EVOLOCUMAB on aldosterone among high cardiovascular risk patients

ACTH stimulation improves the sensitivity of aldosterone to rennin ratio (ARR) for detecting inappropriate aldosterone secretion

The aldosterone renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma

Aldosterone-to-renin ratio as an accurate diagnostic tool in patients on antihypertensive therapy

Androsterone glucuronide does not differ between nonobese and obese Caucasian women with polycystic ovary syndrome despite a higher DHEAS in nonobese subjects

Short term regulation of aldosterone secretion after stimulation and suppression experiments in mice

Study of aldosterone secretion in patients with essential hypertension using a modified suppression test

<i>In vitro</i> expression of human aldosterone synthase and 11-beta hydroxylase

Aldosterone to renin ratio and 24-h urine aldosterone level – suitability assessment in primary hyperaldosteronism prediction

Under-expression of the TWIK-related acid-sensitive K<sup>+</sup> channel 2 (TASK-2) gene is a hallmark of aldosterone producing adenoma causing human primary aldosteronism

Quantitative real time RT-PCR of CYP11B2 (aldosterone synthase) to confirm the diagnosis of aldosterone-producing adenomas

Imaging of adrenal aldosterone synthase expression in patients with primary aldosteronism  a first-in-human study with [<sup>18</sup>F]aldoview PET-CT

Aldosterone induced vascular inflammatory disease: Mechanisms and implications for clinical practice

Severe hypoaldosteronism after unilateral adrenalectomy for aldosteronoma: Case report

Study on the pathogenesis of adrenocortical adenoma with bilateral independent secretion of aldosterone and cortisol: a case report and literature review

Aldosterone measurement in the Diagnosis of primary aldosteronism  comparison between two automated immunoassays and two liquid chromatography tandem mass-spectrometry methods

Severe hyperkalemia and unmasking of renal disease following adrenalectomy for aldosteronoma

GnRH in primary aldosteronism

Role of N-type calcium channel blockers in aldosterone biosynthesis

Mineralocorticoid pathway in newborns: evidence for a physiological renal aldosterone unresponsiveness

8.1. The neuropeptide substance P regulates aldosterone secretion in human adrenals

Aberrant expression of serotonin receptors in an aldosterone- and cortisol-producing adenoma

Familial and phenotypic associations of the aldosterone renin ratio in the general population

Aldosterone deficiency and resistance: The different faces of renal salt loss

<p>Acquired hypoaldosteronism as classified by circulating aldosterone levels: characteristics</p>

Angiotensin-Converting Enzyme (ACE) Level, But Not ACE Gene Polymorphism, Is Associated with Prognosis of COVID-19 Infection: Connection Between Type 2 Diabetes, Hypertension and Renin-Angiontensin-Aldosteron System

Modifying impact of 17-hydroxyprogesterone and sex steroids on mineralocorticoid receptor transactivation by aldosterone

Aldosterone- and cortisol-co-secreting adrenal adenoma in an adolescent girl: a case report

Ferroptosis in human adrenocortical cells and aldosterone-producing adenomas

Evaluation of renin-angiotensin-aldosterone system in patients with asymptomatic primary hyperparathyroidism

Aldosterone and renin plasma levels in young patients with polycystic ovary syndrome

The adrenal glands mass and hypertension with elevated levels of aldosterone: is there an association?

Peculiarities of clinical progression of aldosterone producing adrenal adenoma

Severe adrenal hemorrhage in a hypertensive patient, with high plasma aldosterone and metanephrines

ARR screening using IDS-iSYS aldosterone and direct renin: effects of medication in essential and renovascular hypertension, Cushing's syndrome and primary aldosteronism

Identification of a novel CYP11B2 variant in a family with varying degrees of aldosterone synthase deficiency

Aldosterone, Renin, Sodium and Potassium Excretion in Normotensive Prepubertal Children

microRNA profiling of H295R cells following stimulation of aldosterone production: a bioinformatic study

Aldosterone-induced upregulation of urate transporter 1 may be responsible for hyperuricemia

Fetal and maternal regulation of aldosterone synthase and 11 beta hydroxylase

Zona glomerulosa derived Klotho does not regulate aldosterone synthesis in young mice

Immunoexpressions of CYP11B2 and HSD3B2 in genetically <sup><sub></sub></sup>characterised aldosterone producing adenomas

The functional parameters of renin-angiotensin-aldosterone system in obese patients

Differential effects of aldosterone excess on potassium homeostasis and blood pressure in Asian subjects

Unusual case of aldosterone and cortisol co-secreting adrenal adenoma

Dysregulation of tissue reninangiotensinaldosterone system in obese hypertensive rats

The effect of adrenalectomy on 11beta-hydroxylase(CYP11B1) and aldosterone synthase (CYP11B2) gene expression in the hippocampus

Aldosterone/Renin Ratio as Key Player in the Diagnosis of Primary Hypoaldosteronism in Newborns and Infants

Modulation of adrenocortical aldosterone and cortisol synthesis by <i>in vitro</i> oxidized low density lipoprotein

Early renin recovery after adrenalectomy in patients with aldosterone-producing adenoma - a longitudinal study.

Significance of ACTH stimulation test in the diagnosis of an aldosterone-producing adenoma

Identification of genes mediating dysregulated cell growth in aldosterone-producing adenomas

Role of KCNJ5 mutations in mediating cell growth in aldosterone-producing adenomas

A case of aldosterone-secreting giant adrenal carcinoma: a case report

Evaluation of aldosterone to renin ratio in patients with adrenal incidentalomas and/or hypertension

Distinguishing different subtypes of aldosterone-producing adenoma by histological, immunohistochemical and radiological features; a basis for individualised treatment strategies in primary aldosteronism?

Comparison of plasma aldosterone/signal activity and aldosterone/active signal ratios in different clinical conditions

Hyperthermia differentially affects cortisol and aldosterone secretion under stimulated conditions

Mapping of aldosterone and glucocorticoids in mouse kidney using mass spectrometry imaging

Autonomous aldosterone secretion as a significant cause of arterial hypertension: the effectiveness of targeted therapy

Potential role of mast cells in the physiopathology of aldosterone-producing adenoma

Gene expression responses induced in kidney by aldosterone excess and salt

Excessive bilateral adrenal hyperplasia associated with aldosterone synthase (CYP11B2) deficiency

Early Diagnosis and Management of Aldosterone Synthase Deficiency in Infancy: A Case Report

The pathophysiology of aldosterone-producing adenomas associated with their tumor size: the smaller, the higher expression of CYP11B2

ERK1/2 MAPKs and Wnt signaling pathways are independently involved in adipocyte-mediated aldosterone secretion

A rare synchronous presentation of aldosterone producing adenoma and multifocal papillary thyroid microcarcinoma

Epigenetic control of reninangiotensinaldosterone system in hypertrophic heart

A novel CYP11B2 gene mutation in an Asian family with aldosterone synthase deficiency

Aldosterone-producing adrenocortical carcinoma and alteration of secretion pattern on recurrence: a case report

Aldosterone-producing cells regenerated from mesenchymal stem cells

Localisation of unilateral aldosterone secreting tumours in hypokalaemic hypertensive subjects

Haplotype analysis of the aldosterone synthase (CYP11B2) and 11beta-hydroxylase gene (CYP11B1) locus

Clinical and hormonal evolution of aldosterone synthase deficiency: Is complete remission possible?

Human endothelial cells (HUVECs) potentiate aldosterone secretion from human adrenocortical cells through a PKA independent pathway

Aldosterone induces collagen synthesis <i>via</i> activation of ER1/2 in renal proximal tubular epithelial cells

MicroRNAs regulate aldosterone signaling by post-transcriptional control of mineralocorticoid receptor expression

What is the most appropriate cut-off for post-saline aldosterone in saline suppression test after adrenalectomy?

High prevalence of autonomous aldosterone secretion in patients with type 2 Diabetes Mellitus and arterial hypertension. The effect of SGLT2 inhibitors on renin-angiotensin-aldosterone system

Genetic variation at the CYP11B locus accounts for heritabilities of aldosterone excretion and 11-beta hydroxylase activity

Effect of IL1-receptor antagonist on renin-angiotensin-aldosterone system and hemodynamics in obese individuals

Expression of kisspeptin and its receptor in aldosterone-producing adrenal adenomas

First case in Lebanon of homozygous mutation in CYP 11B2 leading to isolated aldosterone deficiency.

Prevalence rate, characteristics and predictive factors of primary aldosteronism among hypertensive patients who had aldosterone-renin ratio screening in Southern Thailand: A retrospective, cross-sectional study

Aldosterone and pro-atrial natriuretic peptide kinetics in response to rehydration in children with diabetic ketoacidosis

In primary aldosteronism, plasma aldosterone concentration is an independent risk factor for albuminuria, and the higher baseline urinary albumin excretion predicts the less glomerular filtration rate after treatment

Adrenal aldosterone and cortisol levels and their concordance with intervention in patients being investigated for primary hyperaldosteronism

Extra-adrenal aldosterone synthesis and its role in non-classical target tissues

The aldosterone/renin ratio during administration of oral contraceptives with different types of gestogens

The evolution of primary aldosteronism

Double somatic mutations of CTNNB1 and GNA11 in aldosterone producing adenomas (APAs) presenting in puberty, pregnancy or menopause

Comparison of aldosterone measurements during saline suppression tests by immunoassay and liquid chromatography tandem mass spectrometry methods

Pattern of adrenal hormonal secretion in patients with adrenal adenomas: the relevance of aldosterone in arterial hypertension

The PremAldo Study: Impaired Aldosterone Signaling Worsens Renal Sodium Loss in Preterm Infants

Undetectably low blood aldosterone concentrations are prevalent in COVID-19 patients but poorly quantified by chemiluminescent immunoassay

Potassium channels in primary aldosteronism

Appropriateness of aldosterone renin ratio (ARR) testing: A retrospective multicentre audit

Importance of vasopressin and aldosterone for clinical outcome of patients after cardiac arrest

Profiling aldosterone and salt responsive pathways in an inducible hypertensive mouse model

Aldosterone antagonist responsive hypokalaemia, hypercortisolism and colonic pseudo-obstruction

ESE Young Investigator Award

The influence of anticoagulant preservatives, time and posture in renin measurements and estimation of aldosterone to renin ratio (ARR)

Molecular mechanisms in primary aldosteronism

APEX1, a novel, negative regulator of aldosterone synthase activity, differentially binds to a single nucleotide polymorphism in the aldosterone synthase gene and represses transcriptional activity both <i>in vitro</i> and <i>in vivo</i>