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Adrenal Bone Cardiovascular Diabetes Endocrine-Disrupting Chemicals Endocrine-Related Cancer Metabolism Neuroendocrinology Obesity Reproduction Steroid and Steroidogenesis Thyroid

Reproduction Leydig

Estrogen Estradiol Ovaries Testes Sperm Oocyte Leydig Follicular FSH LH Mammary

AISSG Patient/Parent Meeting

A novel repressor mechanism regulating fetal Leydig cell steroidogenesis, pertubation of which resul...

Fetal androgens and determination of adult Leydig cell function.

A novel germline DICER1 mutation in a girl with multinodular goiter and ovarian Sertoli-Leydig cell ...

Loss-of-function and missense mutations in MYRF are a novel cause of autosomal dominant 46,XY Leydig cell hypoplasia and 46,XY gonadal dysgenesis

SGPL1 deficiency, a cause of 46XY DSD and adrenal insufficiency, impairs lipid metabolism and steroidogenesis in Leydig cells

SGPL1 deficiency impairs Leydig cell steroidogenesis and should be considered in 46XY individuals with DSD and adrenal insufficiency

Effect of thyroxine replacement on leydig cell and sertoli cell function in men with hypothyroidism

Resource not read: Query You and Your Hormones

Induction of spermatogenesis in men with gonadotrophin deficiency

NEW UNDERSTANDING OF THE ENDOCRINE EFFECTS OF COVID-19

ENVIRONMENTAL EDCs AND DECLINING MALE REPRODUCTIVE HEALTH

MALE HYPOGONADISM AND TESTOSTERONE REPLACEMENT

Male hypogonadism and ageing: rejuvenating the guidance

Endocrinologist 128 Web Updated

Endocrinologist 144 Web

Endocrinologist 148 Web

Endocrinologist 143 Web

Endocrinologist 131 Web Updated

Effects of Quercetin on mRNA expression of Steroidogenesis genes in Primary Cultures of Interstitial Leydig cells treated with Atrazine

No activating point mutation in Cyclin-Dependent Kinase 4 (CDK4) in pituitary adenomas, insulinomas and Leydig cell tumours

Characterization of murine Leydig cell lines as tools to study androgen synthesis disruption by xenobiotics

Severe elevation of testosterone serum levels as unique finding in occult Sertoli-Leydig ovarian cell tumors

4.3. AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failure

Evaluation of Hormonal Profiles and Autoantibodies Against Sperm and Leydig Cells in Patients after Testicular Torsion Treatment

Effect of prolactin (PRL) and melatonin (Mel) in the regulation of cyclooxygenase 2 (COX2) expression in Syrian hamster Leydig cells

An extraordinary case, Leydig cell tumor in a 6-year-old girl with significantly elevated 17-OH Progesterone

Testicular adrenal rest tumor (TART) in congenital adrenal hyperplasia misdiagnosed as Leydig cell tumor

Previous illicit androgen users display persistently impaired Leydig cell capacity but recovered luteinising hormone secretion

SGPL1 deficiency impairs Leydig cell steroidogenesis and should be considered in 46XY individuals with DSD and adrenal insufficiency

SGPL1 deficiency, a cause of 46XY DSD and adrenal insufficiency, impairs lipid metabolism and steroidogenesis in Leydig cells

SGPL1 deficiency is associated with reduced lipid droplet formation and impaired steroidogenesis in Leydig cells

Effect of melatonin in the phosphorylation of ERK42/44, P38 and JNK46/54, and the expression of c-jun and c-fos in hamster Leydig cells

Deregulation of Sertoli and Leydig cells function in patients with Klinefelter syndrome as evidenced by testis transcriptome analysis

A case of primary Leydig cell hyperplasia presenting as unilateral testicular enlargement and peripheral precocious puberty in a 7-year-old male child

9.5. Leydig cell function in male survivors of childhood cancer: A report from the St Jude lifetime cohort study

A rare cause of Secondary Amenorrhoea: Sertoli-Leydig cell tumour of ovary associated with DICER-1

A Novel Germline <em>DICER1</em> Mutation in a Girl with Multinodular Goiter and Ovarian Sertoli-Leydig Cell Tumor

Loss-Of-Function and Missense Mutations in <em>MYRF</em> are a Novel Cause of Autosomal Dominant 46,XY Leydig Cell Hypoplasia and 46,XY Gonadal Dysgenesis

Female hyperandrogenemia, Think beyond the common: A rare case of ovarian Sertoli-Leydig cell tumour

Ovarian Leydig cell hyperplasia  an unusual cause of hyperandrogenism in a post-menopausal woman with a possible familial link

Exogenous androgens reduce the expression of INSL3, a hormone involved in normal testicular descent, in fetal Leydig cells

Dynamic changes of reproductive hormones in male minipuberty: Temporal dissociation of Leydig- and Sertoli-cell activity

The Case of Combination of Multinodular Goiter and Sertoli-Leydig Cell Ovarian Tumor due to Mutation in <em>DICER1</em> Gene

Cimetidine induces testosterone reduction and impairs leydig cell-microvasculature paracrine interaction in adult rats

Criptorchidism, varicocele, azoospermia and Leydig cell tumor in a couple of identical twins with a unique de novo balanced reciprocal translocation.

Endocrine disruptors target ATP binding cassette transporters in the bloodtestis barrier and impair Leydig cell steroidogenesis

Testicular adrenal rest tumours masquerading as Leydig cell tumours in a 55-year-old man with congenital adrenal hyperplasia

<p>Novel genes leading to congenital hypoadrenalism</p>

Infertile men have frequently Leydig cell dysfunction: study on hypogonadism, vitamin D and bone mass in 5177 subjects

A 20-steroid LC-MS/MS panel to investigate classical and backdoor pathways of androgen biosynthesis in the Leydig cells

The endocrine disruptor Benzo[a]Pyrene inhibits gonadotropin-mediated steroidogenesis in a mouse Leydig tumor cell line

Luteinizing hormone and human chorionic gonadotropin (hCG) action on the same receptor results in different <em>in vitro</em> intracellular signaling in mouse primary Leydig cells

Diabetes type 1 can induce testicular atrophy with Leydig cell hyperplasia and germ cell depletion and therefore prevents reproductive function and fertility in rats

Interpretation of CGM-measured nocturnal hypoglycaemia in congenital hyperinsulinism

Roles of testicular macrophage in Leydig cell proliferation in colony-stimulating factor treated mice

Histological Evaluation of Patients with Partial Gonadal Dysgenesis and <em>NR5A1</em> Mutations: Review in Leydig and Germ Cell Pattern

Isolated progesterone secretion by an ovarian Leydig cell tumour: I, hormonal and immunohistochemical characterization II, effects on the gonadotrope axis

Testicular TGF-β1 system expression and its participation in hypertrophy and hyperplasia of Leydig cells

A novel repressor mechanism regulating fetal Leydig cell steroidogenesis, perturbation of which results in masculinization disorders

Sexual dimorphism in the LH responses to kisspeptin and senktide administration in prepubertal mice

Central precocious puberty developed after treatment of leydig cell tumor: case report

Free vs total testosterone as a marker of Leydig cell function and androgen exposure in obese male adolescents

Protein kinase B (Akt) blockade inhibits LH/hCG-mediated 17,20-lyase, but not 17α-hydroxylase activity of CYP17a1 in mouse Leydig cell steroidogenesis

Presentation, clinical features and long-term follow-up of Leydig cell tumours of the testis: 77 cases from a single center experience

11.12. Lower circulating sertoli and leydig cell hormone levels during puberty in obese boys: a cross-sectional study

Ovarian Leydig Cell Tumor in an 8 Years Old Girl Misdiagnosed as Congenital Adrenal Hyperplasia Due to Elevated 17-Hydroxi-Progesterone

Hyperpigmentation leading to depression in Addisons disease: Case report

A rare cause of primary amenorrhoea: leydig cell hypoplasia - inactivating homozygous mutation in the luteinizing hormone chorionic gonadotropic receptor (LHCGR) in an XY genotype individual